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Tropical Animal Health and Production

, Volume 42, Issue 6, pp 1047–1048 | Cite as

Mycobacterium bovis, but also M. africanum present in raw milk of pastoral cattle in north-central Nigeria

  • Simeon I. B. Cadmus
  • Mohammed K. Yakubu
  • Abdullahi A. Magaji
  • Akinbowale O. Jenkins
  • Dick van Soolingen
Brief Communication

Abstract

Using deletion typing technique, five mycobacteria isolated from unpasteurised milk samples from cows in north-central Nigeria were characterized as Mycobacterium bovis (n = 4) and M. africanum (n = 1). This report emphasizes that transmission between the animal and human reservoir is a serious threat in Nigeria.

Keywords

Mycobacterium bovis Pasteurization Zoonosis Milk Nigeria 

Abbreviations

MTC

Mycobacterium tuberculosis complex

NALC-NaOH

N-acetyl-L-cysteine Sodium hydroxide

NPC

National Population Commission

RD

Regions of difference

TB

Tuberculosis

Notes

Acknowledgments

The authors are immensely grateful to Dr. Kehinde Adesokan and Dr. Charity Agada for technical assistance. We are also grateful to Dr Femi Faleke for his support at the inception of the study.

References

  1. Ayele, W.Y., Neill, S.D., Zinsstag, J., Weiss, M.G. and Pavlik, I., 2004. Bovine tuberculosis: an old disease but a new threat to Africa, International Journal of Tuberculosis and Lung Diseases, 8, 924–937Google Scholar
  2. Byarugaba, F., Etter, E. M. C., Godreuil, S., Grimaud, P., 2009. Pulmonary tuberculosis and Mycobacterium bovis, Uganda. Emerging Infectious Diseases. doi: 10.3201/eid1501.080487 Google Scholar
  3. Cadmus, S.I.B., Palmer, S., Okker, M., Dale, J., Gover, K., Smith, N., Jahans, K., Hewinson, R.G. and Gordon, S.V., 2006. Molecular analysis of human and bovine tubercle bacilli from a local setting in Nigeria, Journal of Clinical Microbiology, 44, 29–34CrossRefPubMedGoogle Scholar
  4. Cadmus, S.I.B. and Adesokan, H.K., 2007. Phenotypic Characterization and spoligotype profiles of Mycobacterium bovis isolated from unpasteurized cows’ milk in Ibadan, Nigeria, Tropical Veterinarian, 25, 65–72Google Scholar
  5. Cameroon, A., 2003. Survey tool for livestock diseases, a practical manual and software package for surveillance in developing countries. Australian Centre for International Agricultural Research (ACIAR) Monograph 54Google Scholar
  6. Hlavsa, M.C., Moonan, P.K., Cowan, L.S., Navin, T.R., Kammerer, J.S., Morlock, G.P., Crawford, J.T., and LoBue, P.A., 2008. Human tuberculosis due to Mycobacterium bovis in the United States, 1995-2005, Clinical Infectious Diseases, 47, 168–175.CrossRefPubMedGoogle Scholar
  7. Leite, C.Q., Anno, I.S., Leite, S.R., Roxo, E., Morlock, G.P. and Cooksey, R.C., 2003. Isolation and identification of Mycobacterium from livestock specimens and milk obtained in Brazil, Memorias do Isntituto Oswaldo Cruz, 98, 319–23CrossRefPubMedGoogle Scholar
  8. Ofukwu, R.A., Oboegbulem, S.I. and Akwuobu, C.A., 2008. Zoonotic Mycobacterium species in fresh cow milk and fresh skimmed, unpasteurised market milk (nono) in Makurdi, Nigeria: implications for public health, Journal of Animal and Plant Science, 1, 21–25Google Scholar
  9. Warren, R.M., Gey van Pittius, N.C., Barnard, M., Hesseling, A., Engelke, E., de Kock, M., Gutierrez, M.C., Chege, G.K., Victor, T.C., Hoal, E.G. and van Helden, P.D., 2006. Differentiation of Mycobacterium tuberculosis complex by PCR amplification of genomic regions of difference, International Journal of Tuberculosis and Lung Diseases, 10, 818–822Google Scholar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Simeon I. B. Cadmus
    • 1
  • Mohammed K. Yakubu
    • 2
  • Abdullahi A. Magaji
    • 2
  • Akinbowale O. Jenkins
    • 3
  • Dick van Soolingen
    • 4
  1. 1.Department of Veterinary Public Health and Preventive MedicineUniversity of IbadanIbadanNigeria
  2. 2.Department of Veterinary Public Health and Animal ProductionFaculty of Veterinary Medicine, Usmanu Danfodiyo UniversitySokotoNigeria
  3. 3.Department of Veterinary Tropical DiseaseFaculty of Veterinary Sciences, University of PretoriaPretoriaSouth Africa
  4. 4.National Institute for Public Health and the Environment (RIVM)BilthovenThe Netherlands

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