Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses
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The present work was conducted to study the comparative efficacy of two anti-protozoan (babesicidal) drugs on the recovery and health of horses. A total of 80 horses, showing typical clinical symptoms of the disease, were selected for this study; the presence of babesiosis was confirmed through blood smear examination. These animals were divided into two groups i.e. A and B. Horses of Group A, were treated with diminazene diaceturate, while horses of Group B were treated with diminazene aceturate. Efficacy of the drugs was determined by the reversal of clinical signs and a negative blood smear examination. The efficacy of diminazene diaceturate was demonstrated to be 80% while diminazene aceturate was found to have 90% efficacy against babesiosis.
KeywordsBabesiosis Babesia caballi Babesia equi Diminazene aceturate Diminazene diaceturate Equine Piroplasmosis
The Authors thank Ansar Abbas and Prix Pharmaceutica, Pakistan for grant of samples of diminazene aceturate to be used in the study.
We are also thankful to Dr. Kim Picozzi, and Sally Uuastling, Centre for Tropical Veterinary Medicine, University of Edinburgh, UK, for editorial assistance.
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