Transgenic Research

, Volume 16, Issue 3, pp 315–332 | Cite as

Production of vaccines and therapeutic antibodies for veterinary applications in transgenic plants: an overview

  • Doreen Manuela Floss
  • Dieter Falkenburg
  • Udo Conrad


During the past two decades, antibodies, antibody derivatives and vaccines have been developed for therapeutic and diagnostic applications in human and veterinary medicine. Numerous species of dicot and monocot plants have been genetically modified to produce antibodies or vaccines, and a number of diverse transformation methods and strategies to enhance the accumulation of the pharmaceutical proteins are now available. Veterinary applications are the specific focus of this article, in particular for pathogenic viruses, bacteria and eukaryotic parasites. We focus on the advantages and remaining challenges of plant-based therapeutic proteins for veterinary applications with emphasis on expression platforms, technologies and economic considerations.


Molecular pharming Plant-based vaccines Therapeutic antibodies Transgenic plants Veterinary medicine 



We wish to thank our colleagues in the Phama-Planta consortium for helpful discussions.


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© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • Doreen Manuela Floss
    • 1
  • Dieter Falkenburg
    • 2
  • Udo Conrad
    • 1
  1. 1.Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)GaterslebenGermany
  2. 2.Novoplant GmbHGaterslebenGermany

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