Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Photocatalytic Cancer (HeLa) Cell-Killing Enhanced with Cu–TiO2 Nanocomposite

Abstract

The metallic Cu nanoparticles have been successfully deposited on the heterogeneous TiO2 surface by the borohydride reduction of copper nitrate in water/CH3CN mixture under Ar atmosphere. The catalytic activity of the Cu–TiO2 nanocomposite was evaluated by the application to a photocatalytic cancer cell-killing under UV–visible light irradiation. Based on the obtained results, a plausible mechanism was proposed.

This is a preview of subscription content, log in to check access.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

References

  1. 1.

    Anpo M, Takeuchi M (2003) J Catal 216:505

  2. 2.

    Dawson A, Kamat PV (2001) J Phys Chem B 105:960

  3. 3.

    Bowker M, James D, Stone P, Bennett R, Perkins N, Millard L, Greaves J, Dickinson A (2003) J Catal 217:427

  4. 4.

    Herrmann JM, Disdier J, Pichat P (1988) J Catal 113:72

  5. 5.

    Stathatos E, Lianos P, Falaras P, Siokou A (2000) Langmuir 16:2398

  6. 6.

    Schaaff TG, Blom DA (2002) Nano Lett 2:507

  7. 7.

    Sun B, Vorontsov AV, Smirniotis PG (2003) Langmuir 19:3151

  8. 8.

    Kim S, Choi W (2002) J Phys Chem B 106:13311

  9. 9.

    Jeon S, Braun PV (2003) Chem Mater 15:1256

  10. 10.

    Klosek S, Raftery D (2001) J Phys Chem B 105:2815

  11. 11.

    Patra A, Friend CS, Kapoor R, Prasad PN (2003) Chem Mater 15:3650

  12. 12.

    Premkumar J (2004) Chem Mater 16:3980

  13. 13.

    Bryan JD, Heald SM, Chambers SA, Gamelin DR (2004) J Am Chem Soc 126:11640

  14. 14.

    Kamat PV (1993) Chem Rev 93:267

  15. 15.

    Bard JA (1982) J Phys Chem 86:172

  16. 16.

    Burgeth G, Kisch H (2002) Coord Chem Rev 230:40

  17. 17.

    Wood A, Giersig M, Mulvaney P (2001) J Phys Chem B 105:8810

  18. 18.

    Jakob M, Levanon H, Kamat PV (2003) Nano Lett 3:353

  19. 19.

    Subramanian V, Wolf EE, Kamat PV (2003) J Phys Chem B 107:7479

  20. 20.

    Choi JY, Kim KH, Choy KC, Oh KT, Kim KN (2007) J Biomed Mater Res A 2:353

  21. 21.

    Cai R, Kubota Y, shuin T, Sakai H, Hashimoto K, Fujishima A (1992) Cancer Res 52:2346

  22. 22.

    Xu ZP, Zeng QH, Lu GQ, Yu AB (2006) Chem Eng Sci 61:1027

  23. 23.

    Bideau M, Claudel B, Faure L, Rachimoellah M (1990) Chem Eng Commun 93:167

  24. 24.

    Okamoto KI, Yamamoto Y, Tanaka H, Tanaka M, Itaya A (1985) Bull Chem Soc Jpn 58:2015

  25. 25.

    Hufschmidt D, Bahnemmann D, Testa JJ, Emilio CA, Litter MI (2002) J Photochem Photobiol A 148:223

  26. 26.

    Abdulla-Al-Mamun M, Kusumoto Y (2009) Chem Lett 38:826

  27. 27.

    Abdulla-Al-Mamun M, Kusumoto Y, Muruganandham M (2009) Mater Lett 63:2007

  28. 28.

    Wagner CD, Riggs WM, Davis LE, Moulder SF, Mullenberg GE (1979) Handbook of X-ray photoelectron spectroscopy. Perkin-Elmer Corporation, Physical Electronics Division, New York

  29. 29.

    Subramanian V, Wolf EE, Kamat PV (2004) J Am Chem Soc 126:4943

  30. 30.

    Harbour JR, Tromp J, Hair ML (1985) Can J Chem 63:204

  31. 31.

    Fujihira M, Satoh Y, Osa T (1981) Nature 293:206

  32. 32.

    Linsebigler AL, Lu G, Yates JT Jr (1995) Chem Rev 95 735

  33. 33.

    Abdulla-Al-Mamun M, Kusumoto Y, Mihata A, Islam MS, Ahmmad B (2009) Photochem Photobiol Sc. 8:1125

Download references

Acknowledgements

The present work was partly supported by Grant-in-Aid for Scientific Research (B) (19360367) from Japan Society for the Promotion of Science (JSPS). The authors wish to thank Prof. Junichi Kurawaki for his informative discussions.

Author information

Correspondence to Yoshihumi Kusumoto.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Abdulla-Al-Mamun, M., Kusumoto, Y., Ahmmad, B. et al. Photocatalytic Cancer (HeLa) Cell-Killing Enhanced with Cu–TiO2 Nanocomposite. Top Catal 53, 571–577 (2010). https://doi.org/10.1007/s11244-010-9489-5

Download citation

Keywords

  • Water/CH3CN mixture
  • Cu–TiO2 nanocomposite
  • Photocatalysis
  • Cancer cell-killing