Solvent-Free Microwave Promoted [3 + 2] Cycloaddition of Alkyne-Azide in Uniform CuO Hollow Nanospheres
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CuO hollow nanospheres on acetylene black (CuO/AB) have been used for the catalytic [3 + 2] cycloaddition of azides with terminal alkynes without solvent, and within 1 min under microwave irradiation. The CuO/AB was readily separated by centrifugation, and could be reused five times under the present reaction conditions without any loss of catalytic activity.
KeywordsMicrowave Copper oxide Acetylene black Heterogeneous Catalyst Click reaction
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2009-0070926) and by the Korean Research Foundation Grant (KRF-2006-312-C00565).