Transition Metal Chemistry

, Volume 43, Issue 1, pp 83–89 | Cite as

Synthesis, crystal structures and biological activities of transition metal complexes of a salen-type ligand

  • Ratnamala S. Bendre
  • Samina K. Tadavi
  • Manohar M. Patil
Article
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Accepted:

Abstract

Manganese(III), cobalt(II), nickel(II) and copper(II) complexes of a salen-type ligand, namely 6,6′-((1E,1′E)-(ethane-1,2-diylbis(azanylylidene))bis(methanylylidene))bis(5-isopropyl-2-methylphenol) (H2L), have been synthesized and characterized by physicochemical and spectroscopic methods. In addition, single-crystal X-ray analysis confirmed the formulae of the manganese and nickel complexes as [Mn(OAc)(L)] and [Ni(L)], respectively. The free Schiff base and its complexes have been screened for in vitro antibacterial activity by colony count methods, and the antioxidant activity was assayed by DPPH radical scavenging. The ability of free H2L and its complexes to mediate DNA cleavage was studied by agarose gel electrophoresis.

Graphical Abstract

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Notes

Acknowledgements

Authors gratefully thank UGC, New Delhi for sanctioning Major Research Project File No. 42 374/2013(SR) and for Rajiv Gandhi National Fellowship for ST Candidates (Grant No. F1 17.1/2013-14/RGNF-2013-14-ST-MAH-45781/(SA-III/WEBSITE)). We are also grateful to IIT Madras for extending help in solving crystal structure of manganese(III) and nickel(II) complexes.

Supplementary material

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  • Ratnamala S. Bendre
    • 1
  • Samina K. Tadavi
    • 1
  • Manohar M. Patil
    • 1
  1. 1.School of Chemical SciencesNorth Maharashtra UniversityJalgaonIndia

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