Transition Metal Chemistry

, Volume 35, Issue 2, pp 159–163 | Cite as

Synthesis, crystal structures and xanthine oxidase inhibitory activities of two copper(II) complexes with Schiff bases

  • Yan-Qin Cui
  • Zhong-Lu You
  • Xiao-Fang Li
  • Xiao-Ling Wang
  • Yu-Ping Ma
  • Che Wang
  • Cheng-Lu Zhang
Article
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Accepted:

Abstract

Two azido-coordinated Schiff base Cu(II) complexes with the formulae [Cu(L1)(N3)]·MeOH and [Cu(L2)(μ1,1-N3)] n , where L1 is the deprotonated form of 2-chloro-2-[(2-ethylaminoethylimino)methyl]phenol, and L2 is the deprotonated form of 2,4-dibromo-6-[(2-dimethylaminoethylimino)methyl]phenol, have been synthesized and characterized by physico-chemical and spectroscopic methods. The X-ray crystal structures of both complexes have been determined. The Cu atom in [Cu(L1)(N3)]·MeOH is four-coordinate in a square planar geometry, while [Cu(L2)(μ1,1-N3)] n is five-coordinate with a square pyramidal geometry. The molecules in [Cu(L1)(N3)]·MeOH are linked by intermolecular O–H···O and N–H···O hydrogen bonds, forming dimers. The molecules in [Cu(L2)(μ1,1-N3)] n are linked through end-on azido bridges, forming one-dimensional chains. The xanthine oxidase inhibitory activities of both complexes were evaluated.

Keywords

MeOH Schiff Base Xanthine Oxidase Allopurinol Methanol Solution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Notes

Acknowledgments

This work was financially supported by the Education Office of Liaoning Province (Project No. 2008T107).

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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Yan-Qin Cui
    • 1
  • Zhong-Lu You
    • 1
  • Xiao-Fang Li
    • 1
  • Xiao-Ling Wang
    • 1
  • Yu-Ping Ma
    • 1
  • Che Wang
    • 1
  • Cheng-Lu Zhang
    • 1
  1. 1.Department of Chemistry and Chemical EngineeringLiaoning Normal UniversityDalianPeople’s Republic of China

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