Journal of Thrombosis and Thrombolysis

, Volume 43, Issue 3, pp 426–427 | Cite as

ST-elevation no myocardial infarction

  • Peter DammanEmail author
  • Robbert J. de Winter
  • Mitchell W. Krucoff
Letter to the Editor

Acute coronary syndrome encompasses a clinical spectrum of signs and symptoms and that are most commonly caused by intracoronary atherosclerotic plaque rupture or erosion with superimposed thrombus formation and distal embolization [1]. This intracoronary thrombus may lead to (partial) occlusion of the artery and a reduction in blood flow leading to clinical symptoms such as chest pain. Despite the common pathophysiological substrate, the clinical presentation of ACS is diverse. It ranges from ST-segment elevation myocardial infarction (STEMI), where the coronary artery is totally occluded by thrombus, to non-ST-segment elevation acute coronary syndrome characterized by a partially or intermittently occlusive thrombus. ST-segment elevation on electrocardiography, indicating but not limited to complete coronary occlusion, is the clinical hallmark of ST-elevation myocardial infarction (STEMI). Although myocardial cell injury can occur after 20–30 min of ischemia, it takes several hours...


Primary Percutaneous Coronary Intervention Coronary Occlusion Myocardial Necrosis Collateral Blood Flow Elevation Acute Coronary Syndrome 
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Compliance with ethical standards

Conflict of interest

None with regards to this article.

Research involving human rights

This article does not contain any studies with human participants performed by any of the authors.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Peter Damman
    • 1
    Email author
  • Robbert J. de Winter
    • 1
  • Mitchell W. Krucoff
    • 2
  1. 1.Department of Cardiology (B2-213)Academic Medical Center – University of AmsterdamAmsterdamThe Netherlands
  2. 2.Duke University Medical CenterDuke Clinical Research InstituteDurhamUSA

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