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Journal of Thrombosis and Thrombolysis

, Volume 35, Issue 2, pp 223–227 | Cite as

Embolic events caused by aortic thrombi: An underestimated entity?

  • Dietrich Stoevesandt
  • Carsten Klempt
  • Robert Scheubel
  • Waldemar Herr
  • Stefan Hettwer
  • Karl Werdan
  • Rolf-Edgar Silber
  • Torsten Kraya
  • Oliver Thews
  • Axel Schlitt
Article

Abstract

Stroke and other thromboembolic events are mainly caused by emboli from heart, aorta and other arteries. In this paper we describe a group of 5 middle-aged patients suffering from emboli caused by large thrombi in the aorta. Since the development of giant thrombi under high flow conditions in the aorta is a pathophysiological process which is not well understood, a model of flow distribution by numerically simulating the Navier–Stokes equation for an incompressible fluid was generated. This model simulated how such thrombi may develop in the aorta. We hypothesize that large thrombi issuing from the aortic vessel wall represent a underestimated entity in middleaged persons and are probably overlooked as the cause of stroke or other embolic events in some cases.

Keywords

Aorta Thrombus Thromboembolic events 

Notes

Acknowledgments

C.K. and W.H. acknowledge support from the Centre for Quantum Engineering and Space–Time Research QUEST.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Dietrich Stoevesandt
    • 1
  • Carsten Klempt
    • 2
  • Robert Scheubel
    • 3
  • Waldemar Herr
    • 2
  • Stefan Hettwer
    • 4
  • Karl Werdan
    • 4
  • Rolf-Edgar Silber
    • 3
  • Torsten Kraya
    • 5
  • Oliver Thews
    • 6
  • Axel Schlitt
    • 4
    • 7
  1. 1.Department for Diagnostic RadiologyMartin-Luther-University Halle-WittenbergHalle (Saale)Germany
  2. 2.Institute of Quantum OpticsLeibniz University HannoverHannoverGermany
  3. 3.Department for Heart and Thoracic SurgeryMartin-Luther-University Halle-WittenbergHalle (Saale)Germany
  4. 4.Department of Medicine IIIMartin-Luther-University Halle-WittenbergHalle (Saale)Germany
  5. 5.Department of NeurologyMartin-Luther-University Halle-WittenbergHalle (Saale)Germany
  6. 6.Institute of PhysiologyMartin-Luther-University Halle-WittenbergHalle (Saale)Germany
  7. 7.Department of CardiologyParacelsus-Harz-Clinic Bad SuderodeBad SuderodeGermany

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