We have conducted a comparative study of thermal (convective) and microwave drying processes for a temperature-sensitive compound, the drug substance cocarboxylase hydrochloride. We have shown that in a microwave field, we observe significant intensification of the drying process in all stages. We have analyzed the reasons for such intensification and we have determined the physical and chemical factors responsible for microwave-accelerated drying of temperature-sensitive organic compounds.
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Voloshko, A.Y., Pinchukova, N.A., Shishkin, O.V. et al. Physical and Chemical Factors in Microwave-Accelerated Drying of Temperature-Sensitive Organic Compounds. Theor Exp Chem 49, 204–211 (2013). https://doi.org/10.1007/s11237-013-9316-8
- microwave radiation
- thermal heating
- drying rate
- moisture transfer
- temperature gradient
- energy consumption