Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Formation of Ethers from Alcohols with Chloride Complexes of Platinum(II) as Catalysts


A new catalytic reaction of the etherification of alcohols in the system ROH-PtCl 4 2− has been observed. At 70 °C in the presence of catalytic amounts of chloride complexes of platinum(II) methanol gave dimethyl ether. Methyl tert-butyl ether and di-tert-butyl ether were formed analogously from a mixture of methanol and tert-butanol. In the reaction with ethanol the products were diethyl ether and a π-ethylene complex of platinum(II). It is suggested that the step-wise mechanism includes the oxidative addition of the alcohol with the intermediate formation of an alkyl complex of platinum(IV), the decomposition of which by reductive elimination under the influence of a second molecule of alcohol or an alkoxide anion gives an ether and regenerates the catalyst, a chloride complex of platinum(II).

This is a preview of subscription content, log in to check access.


  1. 1.

    A. E. Shilov and G. B. Shul’pin, Activation and Catalytic Reactions of Saturated Hydrocarbons in the Presence of Metal Complexes, Kluwer, Boston (2000).

  2. 2.

    J. A. Labinger and J. E. Bercaw, Nature, 417, 507–514 (2002).

  3. 3.

    R. H. Crabtree, J. Chem. Soc., Dalton Trans., 2437–2450 (2001).

  4. 4.

    J. A. Labinger, J. Mol. Catal. A, 220, 27–35 (2004).

  5. 5.

    N. F. Gol’dshleger, V. V. Es’kova, and A. E. Shilov, Zh. Fiz. Khim., 46, 1353 (1972).

  6. 6.

    A. Sen, Accounts Chem. Res., 31, 550–557 (1998).

  7. 7.

    A. C. Hutson, M. Lin, N. Basickes, and A. Sen, J. Organomet. Chem., 504, 69–74 (1995).

  8. 8.

    S. A. Mitchenko and A. A. Shubin, Metallorganic Derivatives of Acido Complexes of Platinum: Synthesis, Reactivity, and Design of Catalytic Reactions [in Russian], DonGUET, Donetsk (2004).

  9. 9.

    G. A. Luinstra, L. Wang, S. S. Stahl, et al., Organometallics, 14, No.1/2, 75–91 (1995).

  10. 10.

    R. West, D. L. Powell, M. K. T. Lee, and L. S. Whatley, J. Am. Chem. Soc., 86, No.16, 3227 (1964).

  11. 11.

    S.-O. Lawesson and N. C. Yang, J. Am. Chem. Soc., 81, No.16, 4230 (1959).

  12. 12.

    G. A. Olah, Y. Halpern, and H. C. Lin, Synthesis, 315 (1975).

  13. 13.

    V. V. Zamashchikov, S. L. Litvinenko, O. N. Uzhik, and V. F. Galat, Koordinats. Khim., 12, No.7, 972–977 (1986).

  14. 14.

    V. V. Zamashchikov, E. S. Rudakov, S. A. Mitchenko, et al., Izv. AN SSSR, Ser. Khim., No. 1, 192–195 (1986).

  15. 15.

    H. E. Bryndza, J. Chem. Soc., Chem. Commun., No. 23, 1696 (1985).

  16. 16.

    I. N. Chernyaev (ed.), Synthesis of Compounds of the Platinum Metal Group [in Russian], Nauka, Moscow (1964).

  17. 17.

    L. Bellamy, Advances in the IR Spectra of Complex Molecules [Russian translation], Mir, Moscow (1971).

Download references

Author information

Additional information


Translated from Teoreticheskaya i Eksperimental’naya Khimiya, Vol. 41, No. 3, pp. 190–193, May–June, 2005.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Mitchenko, S.A., Vdovichenko, A.N., Bezbozhnaya, T.V. et al. Formation of Ethers from Alcohols with Chloride Complexes of Platinum(II) as Catalysts. Theor Exp Chem 41, 203–206 (2005).

Download citation

Key words

  • alcohols
  • ethers
  • catalysis
  • chloride complexes of platinum(II)
  • oxidative addition
  • reductive elimination