Sexual Dysfunction in Multiple Sclerosis
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To describe sexual dysfunction (SD) in persons with MS, its impact on quality of life and relationship with bladder function. Persons with definite MS (n = 73) from a tertiary hospital database, interviewed using standardized measures. For disability: Neurological Disability Scale (NDS), American Urological Association Index, Urogenital Distress Inventory (UDI6), Incontinence Impact Questionnaire (IIQ7) and Personal Experiences Questionnaire (PEQ); participation: Multiple Sclerosis Impact Scale (MSIS). Mean age 50 years, 73% female, 52% progressive MS and 60% with detrusor overactivity. Fifty-one (72%) had PEQ scores indicating SD. Women reported greater SD than men (p = .013). SD included: lack of enjoyment of sexual activity (32%), failure of arousal (30%) and anorgasmia (47%). Patients who reported MS impacted ‘a great deal ‘on their sex lives, compared with those who did not, showed significant differences on PEQ Sexual Frequency (p = .01), IIQ7 (p = .03), UDI6 (p = .04) and both MSIS subscales (Physical p = .04; Psychological p = .03). The PEQ Sexual Frequency scale significantly correlated with NDS (rho = −.30), QoL Bladder score (rho = −.35) and MSIS Physical subscale (rho = −.30). No association was found between SD and age, years since diagnosis, stage or severity of MS. SD is complex and often overlooked in clinical care. Improved management options for SD may improve QoL in these persons.
KeywordsMultiple sclerosis Bladder Sexual dysfunction Participation Multiple Sclerosis Impact Scale Neurological Disability Scale
We thank all persons with MS who participated in this study. We are also grateful to L Oscari for conducting the interviews.
Conflict of Interest
- 1.Foley, F.W., Sanders, A.: Sexuality, multiple sclerosis and women. Mult. Scler. Manag. 1, 1–9 (1997)Google Scholar
- 2.Foley, F., Gimbel, B.: Introduction to intimacy and sexuality in MS. MS in focus, vol. 6, pp. 4–5. Cambridge Publishers Ltd, Cambridge (2005)Google Scholar
- 17.Barry, M.J., Fowler Jr., F.J., O’Leary, M.P., Bruskewitz, R.C., Holtgrewe, H.L., Mebust, W.K., et al.: The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J. Urol. 148(5), 1549–1557 (1992). (discussion 64)PubMedGoogle Scholar
- 18.Shumaker, S.A., Wyman, J.F., Uebersax, J.S., McClish, D., Fantl, J.A.: Health-related quality of life measures for women with urinary incontinence: the Incontinence Impact Questionnaire and the Urogenital Distress Inventory Continence Program in Women (CPW) Research Group. Qual. Life Res. 3(5), 291–306 (1994)PubMedCrossRefGoogle Scholar
- 19.Uebersax, J.S., Wyman, J.F., Shumaker, S.A., McClish, D.K., Fantl, J.A.: Short forms to assess life quality and symptom distress for urinary incontinence in women: the Incontinence Impact Questionnaire and the Urogenital Distress Inventory. Continence Program for Women Research Group. Neurourol. Urodyn. 14(2), 131–139 (1995)PubMedCrossRefGoogle Scholar
- 24.Nunnally, J.C.: Psychometric theory. McGraw-Hill, New York (1978)Google Scholar
- 28.Aisen ML, Sanders AS: Sexual dysfunction in neurologic disease: mechanisms of disease and counseling approaches. AUA update Series Lesson 35 [serial on the Internet]. XV11 (1998)Google Scholar