Aggregation behavior and solubilization properties of 3-hydroxypiperidinium surfactants
- 6 Downloads
Systematic data on the aggregation behavior of novel 3-hydroxypiperidinium surfactants in aqueous solutions were obtained. The ability of the surfactants to solubilize hydrophobic compounds, including the Orange OT dye and biologically active flavonoid quercetin, was characterized. The maximally achieved limiting content of these substances in micellar solutions of 3-hydroxypiperidinium surfactants is by two to three times higher than that in solutions of their non-functionalized analogs. The solubility of quercetin depends on the pH of the medium, and the highest effect observed on going from water to micellar solutions of the studied surfactants reaches two orders of magnitude.
Key wordssurfactants aggregation solubilization drugs
Unable to display preview. Download preview PDF.
- 1.K. R. Lange, Surfactants: A Practical Handbook, Hanser Publishers, Munich, 1999, 237 pp.Google Scholar
- 3.D. Myers, Surfactant Science and Technology, John Wiley and Sons, Hoboken, New Jersey 2006, 380 pp.Google Scholar
- 4.S. Abbott, Surfactant Science. Principles and Practice, DEStech Publishing Inc, Lancaster, Pennsylvania, 2017, 198 pp.Google Scholar
- 6.E. E. Badr, Adv. Appl. Sci Res., 2017, 8, 81.Google Scholar
- 14.V. L. Klimova, Osnovnye mikrometody analiza organicheskikh soedinenii [The Main Methods for Analysis of Organic Compounds], Khimiya, Moscow, 1974, 224 pp. (in Russian).Google Scholar
- 16.A. I. Rusanov, Mitselloobrazovanie v rastvorakh poverkhnostno-aktivnykh veshchestv [Micelle Formation in Solutions of Surfactants], Khimiya, St. Petersburg, 1992, 280 pp. (in Russian).Google Scholar
- 22.I. G. Zenkevich, A. Yu. Eshchenko, S. V. Makarova, A. G. Vitenberg, Yu. G. Dobryakov, V. A. Utsal, Molecules, 2007, 12Google Scholar