Analysis of 3D printing possibilities for the development of practical applications in synthetic organic chemistry
The possibility of rapid manufacturing of customized chemical labware and reactionware by three-dimensional (3D) printing is discussed. The advantages and disadvantages of this approach to the design of chemical equipment from different engineering plastics were demonstrated and the suitability of some materials for chemical applications was estimated: PP > PLA > > ABS > PETG (PP is polypropylene, PLA is polylactide, ABS is acrylonitrile butadiene styrene, and PETG is polyethylene terephthalate glycol). The procedure described is a powerful tool for the production of both typical and unique chemical labware; to date, the fused deposition modeling (FDM) method is already available for the everyday use in chemical laboratories. The examples of successful application of 3D-printed products were demonstrated: solvent resistance and impermeability were assessed, as well as Pd(OAc)2-catalyzed cross-coupling between p-bromotoluene and phenylboronic acid and Ni(acac)2-catalyzed hydrothiolation of alkyne with thiophenol were performed.
Key words3D printing FDM method labware cross-coupling hydrothiolation
Unable to display preview. Download preview PDF.
- 1.V. P. Ananikov, L. L. Khemchyan, Yu. V. Ivanova, V. I. Bukhtiyarov, A. M. Sorokin, I. P. Prosvirin, S. Z. Vatsadze, A. V. Medved’ko, V. N. Nuriev, A. D. Dilman, V. V. Levin, I. V. Koptyug, K. V. Kovtunov, V. V. Zhivonitko, V. A. Likholobov, A. V. Romanenko, P. A. Simonov, V. G. Nenajdenko, O. I. Shmatova, V. M. Muzalevskiy, M. S. Nechaev, A. F. Asachenko, O. S. Morozov, P. B. Dzhevakov, S. N. Osipov, D. V. Vorobyeva, M. A. Topchiy, M. A. Zotova, S. A. Ponomarenko, O. V. Borshchev, Yu. N. Luponosov, A. A. Rempel, A. A. Valeeva, A. Yu. Stakheev, O. V. Turova, I. S. Mashkovsky, S. V. Sysolyatin, V. V. Malykhin, G. A. Bukhtiyarova, A. O. Terent’ev, I. B. Krylov, Russ. Chem. Rev., 2014, 83, 885.CrossRefGoogle Scholar
- 12.Repetier-Host v. 1.5.6., 2011-2015, Hot-World GmbH&Co. KG, Willich, Germany, http://www.repetier.com.Google Scholar