Russian Chemical Bulletin

, 56:2277 | Cite as

Aroyl[bis(4-hydroxycoumarin-3-yl)]methanes in reactions with 1,2-diaminobenzenes

  • N. N. Kolos
  • L. L. Gozalishvili
  • F. G. Yaremenko
  • O. V. Shishkin
  • S. V. Shishkina
  • I. S. Konovalova
Article

Abstract

The reaction of aroyl[bis(4-hydroxycoumarin-3-yl)]methanes with 1,2-phenylenediamines in PriOH is accompanied by the recyclization to 8-R-or 7-R-4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-ones, whereas the reaction with o-phenylenediamine and its 4-methyl-substituted derivatives in MeOH produces organic ionic salts of the bis-coumarin anion with monoprotonated o-phenylenediamine as the cation.

Key words

aroyl[bis(4-hydroxycoumarin-3-yl)]methanes 4-R-1,2-diaminobenzenes 8-R-(7-R)-4-(2-hydroxyphenyl)-1,5-benzodiazepin-2-ones recyclization ionic salts X-ray diffraction study 

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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • N. N. Kolos
    • 1
  • L. L. Gozalishvili
    • 1
  • F. G. Yaremenko
    • 2
  • O. V. Shishkin
    • 3
  • S. V. Shishkina
    • 3
  • I. S. Konovalova
    • 3
  1. 1.V. N. Karazin Kharkov National UniversityKharkovUkraine
  2. 2.V. Ya. Danilevsky Institute of Endocrine Pathology ProblemsAcademy of Medical Sciences of UkraineKharkovUkraine
  3. 3.State Scientific Institution “Institute for Single Crystals”National Academy of Sciences of UkraineKharkovUkraine

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