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Russian Chemical Bulletin

, Volume 54, Issue 4, pp 1032–1037 | Cite as

Synthesis of 3-alkyl-4-aminofurazans

  • A. B. Sheremetev
  • Yu. L. Shamshina
  • D. E. Dmitriev
Article

Abstract

A “one-pot” method for the synthesis of 3-alkyl-4-aminofurazans from ethyl β-alkyl-β-oxopropionates was developed. The multistep process involves hydrolysis of the ester, nitrosation at the activated methylene group, and treatment of the resulting intermediate with an alkaline solution of hydroxylamine in the presence of urea.

Key words

alkylfurazans aminofurazans glyoximes oximes nitrosation cyclization 

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Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • A. B. Sheremetev
    • 1
  • Yu. L. Shamshina
    • 1
  • D. E. Dmitriev
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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