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Research on Chemical Intermediates

, Volume 43, Issue 7, pp 3915–3924 | Cite as

A practical and green protocol for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones using oxalic acid as organocatalyst

  • Shrikrishna Karhale
  • Dattatray Survase
  • Rahul Bhat
  • Panchsheela Ubale
  • Vasant HelaviEmail author
Article

Abstract

An expeditious synthesis of 2,3-dihydroquinazolin-4(1H)-ones in the presence of oxalic acid as an environmentally friendly organocatalyst is reported. The salient features of the protocol are high yields, green reaction profile, shorter reaction times, and simple experimental and work-up procedure.

Graphical Abstract

Keywords

Multi-component reactions Oxalic acid 2,3-Dihydroquinazolin-4(1H)-ones Green protocol 

Notes

Acknowledgements

One of the author (SSK) thankful to UGC, New Delhi, for Teacher Fellowship [F. No. 30-35/14 (WRO) dated: 11th June 2014] under the Faculty Development Programme. Author is also thankful to Principal, Abasaheb Marathe Arts & New Commerce, Science College, Rajapur, Ratnagiri, for encouragement and Head, Department of Chemistry, Rajaram College, Kolhapur for providing necessary facilities.

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Copyright information

© Springer Science+Business Media Dordrecht 2017

Authors and Affiliations

  • Shrikrishna Karhale
    • 1
  • Dattatray Survase
    • 1
  • Rahul Bhat
    • 1
  • Panchsheela Ubale
    • 1
  • Vasant Helavi
    • 1
    Email author
  1. 1.Department of ChemistryRajaram CollegeKolhapurIndia

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