Facile Michael-type addition of aromatic alcohols to N-(4-acetylphenyl)maleic imide
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A one-pot, economical, and efficient synthesis of 1-(4-acetylphenyl)-3-aryloxypyrrolidine-2,5-diones has been accomplished in single steps and in satisfactory yields from 1-(4-acetylphenyl)-pyrrole-2,5-diones and aromatic alcohols. All the compounds were characterized by physical, spectroscopic, and elemental analysis.
KeywordsOxa-Michael adduct N-(4-acetylphenyl)maleic imide Hot water
The authors thank the S.V. National Institute of Technology, Surat, for the financial support, and the members of the analytical group of the Central Salt and Marine Chemicals Research Institute, Bhavnagar, and Oxygen Healthcare Private Ltd, Ahmedabad, Gujarat, India, for spectral measurements.