Reading and Writing

, Volume 20, Issue 1–2, pp 147–171

Genetic and environmental bases of reading and spelling: A unified genetic dual route model

  • Timothy C. Bates
  • Anne Castles
  • Michelle Luciano
  • Margaret J. Wright
  • Max Coltheart
  • Nicholas G. Martin
Article

Abstract

We develop and test a dual-route model of genetic effects on reading aloud and spelling, based on irregular and non-word reading and spelling performance assessed in 1382 monozygotic and dizygotic twins. As in earlier research, most of the variance in reading was due to genetic effects. However, there were three more specific conclusions: the first was that most of the genetic effect is common to both regular and irregular reading. In addition to this common variance evidence was found for distinct genes influencing the acquisition of a lexicon of stored words, and additional genetic effects influencing the acquisition of grapheme–phoneme correspondence rules. The third conclusion, from a combined model of reading and spelling, is that reading and spelling have a common genetic basis. Models that did not distinguish lexical and non-lexical performance fit significantly worse than dual route genetic models. An implication of the research is that models of reading, whether connectionist or dual-route, must allow for the genetic independence of neurological processes underlying the decoding of non-words and irregular words.

Keywords

Dyslexia Genetics Reading Spelling Twins 

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References

  1. Bates T. C., Castles A., Coltheart M., Gillespie N., Wright M., Martin N. G., (2004). Behaviour genetic analyses of reading and spelling: a component processes approach Australian Journal of Psychology 56(2): 115–126CrossRefGoogle Scholar
  2. Bouchard, T. J. J., & Propping, P. (Eds.) (1993). Twins as a tool for behavioral genetics (Vol. Life Sciences Research Report 53). Chichester: John Wiley & SonsGoogle Scholar
  3. Byrne B., Wadsworth S., Corley R., Samuelsson S., Quain P., DeFries J. C., et al., (2005). Longitudinal twin study of early literacy development: Preschool and kindergarten phases Scientific Studies of Reading 9: 219–235CrossRefGoogle Scholar
  4. Castles A., Coltheart M., (1993). Varieties of developmental dyslexia Cognition 47(2): 149–180CrossRefGoogle Scholar
  5. Coltheart M., (1978). Lexical access in simple reading tasks In Underwood G., (Ed.), Strategies of information processing Academic Press LondonGoogle Scholar
  6. Coltheart M., Curtis B., Atkins P., Haller M., (1993). Models of reading aloud: Dual-route and parallel-distributed-processing approaches Psychological Review 100(4): 589–608CrossRefGoogle Scholar
  7. Coltheart M., Rastle K., Perry C., Langdon R., Ziegler J., (2001). DRC: A dual route cascaded model of visual word recognition and reading aloud Psychological Review 108(1): 204–256CrossRefGoogle Scholar
  8. DeFries J. C., Fulker D. W., LaBuda M. C., (1987). Evidence for a genetic aetiology in reading disability of twins Nature 329(6139): 537–539CrossRefGoogle Scholar
  9. DeFries J. C., Stevenson J., Gillis J. J., Wadsworth S. J., (1991). Genetic etiology of spelling deficits in the Colorado and London twin studies of reading disability Reading & Writing 3(3–4): 271–283CrossRefGoogle Scholar
  10. Ellis A. W., (1982). Normality and pathology in cognitive functions Academic Press LondonGoogle Scholar
  11. Gayan J., Olson R. K., (2001). Genetic and environmental influences on orthographic and phonological skills in children with reading disabilities Developmental Neuropsychology 20(2): 483–507CrossRefGoogle Scholar
  12. Gayan J., Olson R. K., (2003). Genetic and environmental influences on individual differences in printed word recognition Journal of Experimental Child Psychology 84(2): 97–123CrossRefGoogle Scholar
  13. Grigorenko E. L., Wood F. B., Meyer M. S., Pauls J. E., Hart L. A., Pauls D. L., (2001). Linkage studies suggest a possible locus for developmental dyslexia on chromosome 1p American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 105(1): 120–129CrossRefGoogle Scholar
  14. Harm M. W., Seidenberg M. S., (2001). Are there orthographic impairments in phonological dyslexia? Cognitive Neuropsychology 18(1): 71–92CrossRefGoogle Scholar
  15. Houghton G., Zorzi M., (2003). Normal and impaired spelling in a connectionist dual-route architecture Cognitive Neuropsychology 20(2): 115–162CrossRefGoogle Scholar
  16. Jinks J. L., Fulker D. W. (1970). A comparison of the biometrical genetic, MAVA, and classical approaches to the analysis of human behaviour. Psychological Bulletin, 73 311–349CrossRefGoogle Scholar
  17. Kendler K. S., Neale M. C., Kessler R. C., Heath A. C., Eaves L. J. (1993). A test of the equal-environment assumption in twin studies of psychiatric illness. Behavior Genetics 23 21–27CrossRefGoogle Scholar
  18. Martin N. G., Eaves L. J., (1977). The genetical analysis of covariance structure Heredity 38(1): 79–95Google Scholar
  19. McGregor B., Pfitzner J., Zhu G., Grace M., Eldridge A., Pearson J., et al., (1999). Genetic and environmental contributions to size, color, shape, and other characteristics of melanocytic naevi in a sample of adolescent twins Genetic Epidemiology 16(1): 40–53CrossRefGoogle Scholar
  20. Morton J., Patterson K., (1987). A new attempt at an interpretation, or, an attempt at a new interpretation In Coltheart M., Patterson K., Marshall J.C., (Eds.), Deep dyslexia (2 ed.). Routledge and Kegan Paul Londonpp. 91–118Google Scholar
  21. Neale, M. C., Boker, S. M., Xie, G. & Maes, H. H. (2002). Mx: Statistical modelling (6th ed.). VCU Box 900126, Richmond, VA 23298: Department of PsychiatryGoogle Scholar
  22. Neale, M. C. & Cardon, L. R. (1992). Methodology for genetic studies of twins and families (Vol. 67). Kluwer Academic PublishersGoogle Scholar
  23. Nothen M. M., Schulte-Korne G., Grimm T., Cichon S., Vogt I. R., Muller-Myhsok B., et al., (1999). Genetic linkage analysis with dyslexia: evidence for linkage of spelling disability to chromosome 15 European Child and Adolescent Psychiatry 8(Suppl 3): 56–59CrossRefGoogle Scholar
  24. Petryshen T. L., Kaplan B. J., Fu Liu M., de French N. S., Tobias R., Hughes M. L., et al., (2001). Evidence for a susceptibility locus on chromosome 6q influencing phonological coding dyslexia American Journal of Medical Genetics 105(6): 507–517CrossRefGoogle Scholar
  25. Plaut D. C., McClelland J. L., Seidenberg M. S., Patterson K., (1996). Understanding normal and impaired word reading: Computational principles in quasi-regular domains Psychological Review 103(1): 56–115CrossRefGoogle Scholar
  26. Plomin R., DeFries J. C., McClearn G. E., McGuffin P., (2001). Behavioral genetics (4 ed.) Worth Publishers New YorkGoogle Scholar
  27. Schulte-Körne G., Grimm T., Nothen M. M., Muller-Myhsok B., Cichon S., Vogt I. R., et al., (1998). Evidence for linkage of spelling disability to chromosome 15 American Journal of Human Genetics 63(1): 279–282CrossRefGoogle Scholar
  28. Seidenberg M. S., McClelland J. L., (1989). A distributed, developmental model of word recognition and naming Psychological Review 96(4): 523–568CrossRefGoogle Scholar
  29. Stevenson J., Graham P., Fredman G., McLoughlin V., (1987). A twin study of genetic influences on reading and spelling ability and disability Journal of child psychology and psychiatry 28(2): 229–247CrossRefGoogle Scholar
  30. Tiu R. D., Wadsworth S. J., Olson R. K., DeFries J. C., (2004). Causal models of reading disability: a twin study Twin Research 7(3): 275–283CrossRefGoogle Scholar
  31. Trouton A., Spinath F. M., & Plomin, R. (2002). Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Research 5: 444–448CrossRefGoogle Scholar
  32. Wright M., Martin N. G., (2003). The Brisbane Adolescent Twin Study: outline of study methods and research projects Australian Journal of Psychology 56 65–78CrossRefGoogle Scholar
  33. Wright M. J., De Geus E., Ando J., Luciano M., Posthuma D., Ono Y., et al., (2001). Genetics of cognition: outline of a collaborative twin study Twin Research 4(1): 48–56CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Timothy C. Bates
    • 1
    • 4
  • Anne Castles
    • 2
  • Michelle Luciano
    • 3
  • Margaret J. Wright
    • 3
  • Max Coltheart
    • 1
  • Nicholas G. Martin
    • 3
  1. 1.Macquarie Centre for Cognitive ScienceMacquarie UniversitySydneyAustralia
  2. 2.Department of PsychologyUniversity of MelbourneMelbourneAustralia
  3. 3.Genetic Epidemiology LaboratoryQueensland Institute of Medical ResearchBrisbaneAustralia
  4. 4.Department of PsychologyUniversity of EdinburghEdinburghUK

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