Quality of Life Research

, Volume 28, Issue 1, pp 99–107 | Cite as

Primary dysmenorrhea with and without premenstrual syndrome: variation in quality of life over menstrual phases

  • Farideh Quick
  • Sakineh Mohammad-Alizadeh-CharandabiEmail author
  • Mojgan Mirghafourvand



The majority of studies on quality of life (QoL) of women with menstrual disturbances have not taken menstrual cycle phase into account. We aimed to determine the size of changes in QoL score during perimenstrual week compared to those during late follicular phase in women suffering from dysmenorrhea with or without premenstrual syndrome (PMS) and also to compare the two groups.


In this observational analytical study, participants were selected purposively from among single students aged 18–30 years, who were residing at university dormitories in Tabriz, Iran, and had moderate or severe dysmenorrhea. They reported quality of their life during the past week using the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF) at two time points, days 3–4 and 11–12, of their menstrual cycle.


Among 52 participants with PMS and 64 without PMS, about half reported severe dysmenorrhea. The mean total quality score was significantly lower during perimenstrual week than during late follicular phase in both group with PMS [48 vs 79, mean difference − 31 (95% confidence interval − 37 to − 26)] and group without PMS [56 vs 78, − 1 (− 27 to − 18)]. The score was significantly lower in the group with PMS than in those without PMS during perimenstrual week [− 8 (− 13 to − 2)] but not during late follicular phase [2.1 (− 2.9 to 7.0)].


Dysmenorrhea with or without PMS significantly reduces QoL of women during perimenstrual week. The QoL is slightly lower in group with PMS during perimenstrual week but not during late follicular phase.


Primary dysmenorrhea Premenstrual syndrome Quality of life Pain Menstrual phase 



This paper has been extracted from thesis of MSc student in Midwifery. Appreciation goes to research deputy of the Tabriz University of Medical Sciences for their financial support. This project was approved by ethics committee of the university (Ethical Code: TBZMED.rec.1394.881, Date 2016-01-04). We send our deep appreciation to all students who patiently participated in this study.

Author Contributions

All of the authors contributed to the conception and design of the study. FQ recruited the participants, collected the data, and wrote the first draft of the paper. FQ and SMAC analyzed the data. SMAC and MM revised the manuscript. All the authors read and approved the final manuscript.


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Students’ Research Committee, Faculty of Nursing and MidwiferyTabriz University of Medical SciencesTabrizIran
  2. 2.Social Determinants of Health Research Center, Faculty of Nursing and MidwiferyTabriz University of Medical SciencesTabrizIran

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