Quality of Life Research

, Volume 25, Issue 8, pp 1969–1979 | Cite as

Changes in quality of life after a diagnosis of cancer: a 2-year study comparing breast cancer and melanoma patients

  • M. Bourdon
  • M. Blanchin
  • P. Tessier
  • M. Campone
  • G. Quéreux
  • F. Dravet
  • V. Sébille
  • A. Bonnaud-Antignac
Article
First Online:
Accepted:

Abstract

Purpose

Longitudinal studies addressing change in health-related quality of life (HRQoL) following a diagnosis of cancer have mainly focused on a single cancer type, and little is known about the differences in HRQoL over time according to the type of tumor. The current study aims to compare the change in HRQoL over 2 years following breast cancer or melanoma diagnosis and socio-demographic variables associated with HRQoL over time.

Methods

Patients recently diagnosed with breast cancer (n = 215) or melanoma (n = 78) completed surveys within 1 month of diagnosis and 6, 12, and 24 months later. Multilevel modeling analyses were used to compare the evolution over time of HRQoL dimensions, as measured by the EORTC QLQ-C30, in both cancers. Longitudinal effect of socio-demographic variables on HRQoL was also assessed.

Results

Consistent with the literature, both cancer patients experienced decreased HRQoL scores following the diagnosis before improving over time. However, our analyses revealed that this rebound effect may occur at diverse times over the course of the illness according to the type of cancer. In addition, HRQoL over time was positively associated with age and negatively related to living with a partner regardless of the type of cancer.

Conclusions

The results of the present study suggest that support in hospital units should be specific and depend on the cancer type.

Keywords

Oncology Longitudinal study Breast cancer Melanoma Health-related quality of life 
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Notes

Acknowledgments

The authors would like to extend their sincere thanks to the patients who agreed to take part in the study. They would also like to thank the Ligue Nationale contre le Cancer for its financial support and the Plateforme nationale «Qualité de vie et cancer».

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Härtl, K., Schennach, R., Müller, M., Engel, J., Reinecker, H., Sommer, H., et al. (2010). Quality of life, anxiety, and oncological factors: A follow-up study of breast cancer patients. Psychosomatics, 51(2), 112–123.CrossRefPubMedGoogle Scholar
  2. 2.
    Høyer, M., Johansson, B., Nordin, K., Bergkvist, L., Ahlgren, J., Lidin-Lindqvist, A., et al. (2011). Health-related quality of life among women with breast cancer: A population-based study. Acta Oncologica, 50(7), 1015–1026.CrossRefPubMedGoogle Scholar
  3. 3.
    Lee, E. S., Lee, M. K., Kim, S. H., Ro, J. S., Kang, H. S., Kim, S. W., et al. (2011). Health-related quality of life in survivors with breast cancer 1 year after diagnosis compared with the general population: A prospective cohort study. Annals of Surgery, 253(1), 101–108.CrossRefPubMedGoogle Scholar
  4. 4.
    Jansen, L., Koch, L., Brenner, H., & Arndt, V. (2010). Quality of life among long-term (≥5 years) colorectal cancer survivors—Systematic review. European Journal of Cancer, 46(16), 2879–2888.CrossRefPubMedGoogle Scholar
  5. 5.
    Klein, D., Mercier, M., Abeilard, E., Puyraveau, M., Danzon, A., Dalstein, V., et al. (2011). Long-term quality of life after breast cancer: A French registry-based controlled study. Breast Cancer Research and Treatment, 129(1), 125–1234.CrossRefPubMedGoogle Scholar
  6. 6.
    Schmidt, M. E., Chang-Claude, J., Vrieling, A., Heinz, J., Flesch-Janys, D., & Steindorf, K. (2012). Journal of Cancer Survivorship, 6(1), 11–19.CrossRefPubMedGoogle Scholar
  7. 7.
    Lehto, U. S., Ojanen, M., & Kellokumpu-Lehtinen, P. (2005). Predictors of quality of life in newly diagnosed melanoma and breast cancer patients. Annals of Oncology, 16(5), 805–816.CrossRefPubMedGoogle Scholar
  8. 8.
    Engel, J., Schlesinger-Raab, A., Emeny, R., Hölzel, D., & Schubert-Fritschle, G. (2014). Quality of life in women with localised breast cancer or malignant melanoma two years after initial treatment: A comparison. International Journal of Behavioral Medicine, 21(3), 478–486.CrossRefPubMedGoogle Scholar
  9. 9.
    Kasparian, N. A., McLoone, J. K., & Butow, P. N. (2009). Psychological responses and coping strategies among patients with malignant melanoma: A systematic review of the literature. Archives of Dermatology, 145(12), 1415–1427.CrossRefPubMedGoogle Scholar
  10. 10.
    Vurnek, Z. M., Buljan, M., Blajić, I., & Situm, M. (2008). Psychological status and illness perceptions in patients with melanoma. Collegium Antropologicum, 32(2), 75–78.Google Scholar
  11. 11.
    Schou, I., Ekeberg, O., Sandvik, L., Hjermstad, M. J., & Ruland, C. M. (2005). Multiple predictors of health-related quality of life in early stage breast cancer. Data from a year follow-up study compared with the general population. Quality of Life Research, 14(8), 1813–1823.CrossRefPubMedGoogle Scholar
  12. 12.
    Härtl, K., Engel, J., Herschbach, P., Reinecker, H., Sommer, H., & Friese, K. (2010). Personality traits and psychosocial stress: Quality of life over 2 years following breast cancer diagnosis and psychological impact factors. Psycho-Oncology, 19(2), 160–169.CrossRefPubMedGoogle Scholar
  13. 13.
    King, M. T., Kenny, P., Shiell, A., Hall, J., & Boyages, J. (2000). Quality of life three months and one year after first treatment for early stage breast cancer: Influence of treatment and patient characteristics. Quality of Life Research, 9(7), 789–800.CrossRefPubMedGoogle Scholar
  14. 14.
    Cormier, J. N., Cromwell, K. D., & Ross, M. I. (2012). Health-related quality of life in patients with melanoma: Overview of instruments and outcomes. Dermatologic Clinics, 30(2), 245–254.CrossRefPubMedGoogle Scholar
  15. 15.
    Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., et al. (1993). The European Organisation for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute, 85(5), 365–376.CrossRefPubMedGoogle Scholar
  16. 16.
    Fayers, P. M., Aaronson, N. K., Bjordal, K., Groenvold, M., Curran, D., Bottomley, A., et al. (2001). The EORTC QLQ-C30 Scoring Manual (3rd ed.). Brussels: European Organisation for Research and Treatment of Cancer.Google Scholar
  17. 17.
    Akaike, H. (1974). A new look at the statistical model identification. System identification and time-series analysis. IEEE Transactions on Automatic Control, 19(6), 716–723.CrossRefGoogle Scholar
  18. 18.
    INCa. (2014). La vie deux ans après un diagnostic de cancer: De l’annonce à l’après cancer [Life two years after a diagnosis of cancer: From the diagnosis to the post-cancer times]. http://www.inserm.fr/…/rapport_complet_la-vie-2-ans-apres-un-diagnostic-de-cancer-2014-2.pdf. Accessed 03 June 2015.
  19. 19.
    Le Coroller-Soriano, A. G., Bouhnik, A. D., Préau, M., Malavolti, L., Julian-Reynier, C., Auquier, P., et al. (2010). Does cancer survivors’ health-related quality of life depend on cancer type? Findings from a large French national sample 2 years after cancer diagnosis. European Journal of Cancer Care, 20(1), 132–140.CrossRefGoogle Scholar
  20. 20.
    Al-Shakhli, H., Harcourt, D., & Kenealy, J. (2006). Psychological distress surrounding diagnosis of malignant and nonmalignant skin lesions at a pigmented lesion clinic. Journal of Plastic, Reconstructive and Aesthetic Surgery, 59(5), 479–486.CrossRefPubMedGoogle Scholar
  21. 21.
    Montazeri, A., Vahdaninia, M., Harirchi, I., Ebrahimi, M., Khaleghi, F., & Jarvandi, S. (2008). Quality of life in patients with breast cancer before and after diagnosis: An eighteen months follow-up study. BMC Cancer. doi: 10.1186/1471-2407-8-330.Google Scholar
  22. 22.
    Rottmann, N., Dalton, S. O., Christensen, J., Frederiksen, K., & Johansen, C. (2010). Self-efficacy, adjustment style and well-being in breast cancer patients: A longitudinal study. Quality of Life Research, 19(6), 827–836.CrossRefPubMedGoogle Scholar
  23. 23.
    Ashing-Giwa, K. T., & Lim, J. W. (2009). Examining the impact of socioeconomic status and socioecologic stress on physical and mental health quality of life among breast cancer survivors. Oncology Nursing Forum, 36(1), 79–88.CrossRefPubMedGoogle Scholar
  24. 24.
    Short, P. F., & Mallonee, E. L. (2006). Income disparities in the quality of life of cancer survivors. Medical Care, 44(1), 16–23.CrossRefPubMedGoogle Scholar
  25. 25.
    Tessier, P., Lelorain, S., & Bonnaud-Antignac, A. (2012). A comparison of the clinical determinants of health-related quality of life and subjective well-being in long-term breast cancer survivors. European Journal of Cancer Care, 21(5), 692–700.CrossRefPubMedGoogle Scholar
  26. 26.
    Kornblith, A. B., Powell, M., Regan, M. M., Bennett, S., Krasner, C., & Moy, B. (2007). Long-term psychosocial adjustment of older vs. younger survivors of breast and endometrial cancer. Psycho-Oncology, 16(10), 895–903.CrossRefPubMedGoogle Scholar
  27. 27.
    Kroenke, C. H., Rosner, B., Chen, W. Y., Kawachi, I., Colditz, G. A., & Holmes, M. D. (2004). Functional impact of breast cancer by age at diagnosis. Journal of Clinical Oncology, 22(10), 1849–1856.CrossRefPubMedGoogle Scholar
  28. 28.
    Lam, W. W., Li, W. W., Bonanno, G. A., Mancini, A. D., Chan, M., Or, A., et al. (2012). Trajectories of body image and sexuality during the first year following diagnosis of breast cancer and their relationship to 6 years psychosocial outcomes. Breast Cancer Research and Treatment, 131(3), 957–967.CrossRefPubMedGoogle Scholar
  29. 29.
    Rosenberg, S. M., Tamimi, R. M., Gelber, S., Ruddy, K. J., Kereakoglow, S., Borges, V. F., et al. (2013). Body image in recently diagnosed young women with early breast cancer. Psycho-Oncology, 22(8), 1849–1855.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • M. Bourdon
    • 1
    • 2
  • M. Blanchin
    • 1
  • P. Tessier
    • 1
  • M. Campone
    • 2
  • G. Quéreux
    • 3
  • F. Dravet
    • 2
  • V. Sébille
    • 1
  • A. Bonnaud-Antignac
    • 1
    • 2
  1. 1.EA 4275-SPHERE methodS for Patients-centered outcomes and HEalth REsearchUniversité de Nantes, UFR des Sciences PharmaceutiquesNantes Cedex 1France
  2. 2.Institut de Cancérologie de l’Ouest, Site René GauducheauSaint Herblain CedexFrance
  3. 3.Unité de Cancéro-dermatologieCentre Hospitalier Universitaire de NantesNantes Cedex 1France

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