The emotional distress of children with cancer in China: an item response analysis of C-Ped-PROMIS Anxiety and Depression short forms
- 481 Downloads
The pediatric patient-reported outcomes measurement information system (PROMIS) was developed to provide self-reported item banks and short forms for children and adolescents (aged 8–17 years) experiencing a chronic illness to assess their quality of life and symptoms. The pediatric PROMIS short forms have been translated into Chinese and applied in children with cancer in China. This study aimed to describe psychometric properties of the Anxiety and Depression measures.
A total of 232 children and adolescents with cancer were recruited in hospital-based inpatient and outpatient clinics. Eight Chinese versions of pediatric PROMIS (C-Ped-PROMIS) measures were administered. Categorical confirmatory factor analysis (CCFA) were conducted to evaluate scale dimensionality and item local dependence of the C-Ped-PROMIS Anxiety and Depression items. Multiple indicator multiple cause models were used to analyze differential item functioning (DIF), item response theory parameters were calculated, and test information against T scores was reported for each measure.
The results of the CCFA confirmed that both C-Ped-PROMIS Anxiety and Depression scales appropriately measure the theoretical constructs as designed. No significant DIF was found for the items of the two scales according to age and gender. Both scales have high test reliability as long as their T scores are not on the low or high extremes.
The pediatric PROMIS Anxiety and Depression measures were developed to provide efficient and flexible assessment of emotional distress domains. Our results provide evidence that the two C-Ped-PROMIS measures can be readily applied to measure anxious and depressive symptoms in Chinese children with cancer.
KeywordsPROMIS Anxiety Depression PRO IRT Pediatrics
Patient-reported outcomes measurement information system
Chinese version of pediatric PROMIS
Quality of life
Categorical confirmatory factor analysis
Item response theory
Multiple indicator multiple cause
Differential item function
This study was supported by the Science and Technology Commission of Shanghai Municipality, China (Project No. 12410707900) and Oncology Nursing Society (ONS) Foundation.
- 1.Cella, D., Yount, S., Rothrock, N., Gershon, R., Cook, K., Reeve, B., et al. (2007). The patient-reported outcomes measurement information system (PROMIS): Progress of an NIH roadmap cooperative group during its first two years. Medical Care, 45(Suppl 1), S3–S11.PubMedCentralPubMedCrossRefGoogle Scholar
- 2.Reeve, B. B., Hays, R. D., Bjorner, J. B., Cook, K. F., Crane, P. K., Teresi, J. A., et al. (2007). Psychometric evaluation and calibration of health-related quality of life item banks: Plans for the patient-reported outcomes measurement information system (PROMIS). Medical Care, 45(5 Suppl 1), S22–S31.PubMedCrossRefGoogle Scholar
- 5.Irwin, D. E., Varni, J. W., Yeatts, K., & DeWalt, D. A. (2009). Cognitive interviewing methodology in the development of a pediatric item bank: A patient reported outcomes measurement information system (PROMIS) study. Health and Quality of Life Outcomes, 7, 3.PubMedCentralPubMedCrossRefGoogle Scholar
- 9.DeWitt, E. M., Stucky, B. D., Thissen, D., Irwin, D. E., Langer, M., Varni, J. W., et al. (2011). Construction of the eight-item patient-reported outcomes measurement information system pediatric physical function scales: Built using item response theory. Journal of Clinical Epidemiology, 64(7), 794–804.PubMedCentralPubMedCrossRefGoogle Scholar
- 15.Lu, Y., Tian, Q., Hao, Y., Jing, J., Lin, Y., & Huang, D. (2008). Reliability and validity for Chinese version of Pediatric Quality of Life Inventory PedsQL4.0. Sun Yat-sen University of Medical Sciences, 29(3), 328–331.Google Scholar
- 16.Zhang, J. W. (2009). Using and assessment of reliability and validity for PedsQL3.0. Guangzhou: Sun Yat-Sen University.Google Scholar
- 17.Wu, M., Xu, L., Zhang, B., Shen, N., & Lu, H. (2009). The level of cancer related fatigue and its related factor of children with acute leukemia. Chinese Journal of Nursing, 44(5), 471–474.Google Scholar
- 18.Wang, X., Tan, J., & Wu, X. (2011). The analysis of influencing factors of quality of life of children with acute lymphocytic leukemia in maintenance treatment. Chinese Journal of Nursing, 46(6), 544–547.Google Scholar
- 19.Varni, J. W., Burwinkle, T. M., Katz, E. R., Meeske, K., & Dickinson, P. (2002). The PedsQL in pediatric cancer: Reliability and validity of the Pediatric Quality of Life Inventory Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer, 94(7), 2090–2106.PubMedCrossRefGoogle Scholar
- 20.Liu, Y., Hinds, P. S., Wang, J., Correia, H., Du, S., Ding, J., et al. (2013). Translation and linguistic validation of the pediatric patient-reported outcomes measurement information system measures into simplified chinese using cognitive interviewing methodology. Cancer Nursing, 36(5), 368–376.PubMedCrossRefGoogle Scholar
- 22.Liu, Y., Shen, Y., Yu, X., Qiu, Y., & Yuan, C. (2013). Analysis of known-group validity of pediatric patient-reported outcomes measurement information system. Nursing Journal of Chinese PLA, 30(6), 18–21.Google Scholar
- 23.Hill, C. D., Edwards, M. C., Thissen, D., Langer, M. M., Wirth, R. J., Burwinkle, T. M., et al. (2007). Practical issues in the application of item response theory: A demonstration using items from the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales. Medical Care, 45, S39–S47.PubMedCrossRefGoogle Scholar
- 24.Muthén, L., & Muthén, B.(1998–2012). Mplus user’s guide. Los Angeles, CA: Muthen & Muthen.Google Scholar
- 26.Muthén, B. (1985). A method for studying the homogeneity of test items with respect to other relevant variables. Journal of Educational Statistics, 10, 121–132.Google Scholar
- 29.Samejima, F. (1969). Estimation of latent ability using a response pattern of graded scores, Psychometrika Monograph, 17, 1–100.Google Scholar
- 31.Muthèn, B. (2013). IRT in Mplus. Mplus Web note (http://www.statmodel.com/download/MplusIRT2.pdf).Accessed. October 28, 2014.
- 34.Thissen, D. (2000). Reliability and measurement precision. In H. Wainer (Ed.), Computerized adaptive testing: A primer (2nd ed., pp. 159–183). Mahwah, NJ: Lawrence Erlbaum Associates.Google Scholar
- 36.Watson, D., Clark, L. A., Weber, K., Assenheimer, J. S., Strauss, M. E., & McCormick, R. A. (1995). Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. Journal of Abnormal Psychology, 104, 15–25.PubMedCrossRefGoogle Scholar