Quality of Life Research

, Volume 23, Issue 8, pp 2319–2326

The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China

  • Yanlei Zhang
  • Jianping Sun
  • Zengchang Pang
  • Xiaoyong Wang
  • Weiguo Gao
  • Feng Ning
  • Jie Ren
  • Anil Kapur
  • Harri Sintonen
  • Qing Qiao



To examine and compare health-related quality of life (HRQoL) in people with previously known diabetes, new screen-detected asymptomatic diabetes and people without diabetes.


HRQoL of 4,613 individuals who participated in a population-based cross-sectional diabetes survey in Qingdao, China, in 2009, was assessed using the 15D instrument. A Tobit regression model to estimate the effects of diabetes on HRQoL separate from effects of other health determinants was constructed.


Among the surveyed population, 220 (4.8 %) individuals had previously known diabetes and 531 (11.5 %) individuals had new screen-detected diabetes, defined by fasting plasma glucose ≥7.0 mmol/l and/or 2-h plasma glucose ≥11.1 mmol/l. The age-, gender-, and BMI-adjusted mean 15D score of people without diabetes, with new screen-detected diabetes, and previously known diabetes was 0.975, 0.975, and 0.964, respectively, for urban and 0.971, 0.972, and 0.960, respectively, for rural participants. HRQoL overall and on all the dimensions (p < 0.05) except for hearing, eating, and speech was worse in the people with previously known diabetes compared to those with new screen-detected diabetes and those without diabetes. Compared to people without diabetes, people with new screen-detected diabetes were worse off on the dimension of usual activities (p < 0.05). After adjusting for comorbid diseases and other confounders, the impact of diabetes on reduced HRQoL was diminished.


Health-related quality of life was impaired in people with previously known diabetes who had co-morbid conditions, but was largely unaltered in people with newly detected asymptomatic diabetes as compared to people without diabetes.


Health-related quality of life 15D instrument Diabetes 


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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Yanlei Zhang
    • 1
  • Jianping Sun
    • 2
  • Zengchang Pang
    • 2
  • Xiaoyong Wang
    • 3
  • Weiguo Gao
    • 4
  • Feng Ning
    • 2
  • Jie Ren
    • 5
  • Anil Kapur
    • 6
  • Harri Sintonen
    • 1
  • Qing Qiao
    • 1
    • 7
  1. 1.Department of Public Health, Hjelt InstituteUniversity of HelsinkiHelsinkiFinland
  2. 2.Qingdao Municipal Centre for Disease Control and PreventionQingdaoChina
  3. 3.Provincial Hospital Affiliated to Shandong UniversityJinanChina
  4. 4.AstraZenecaShanghaiChina
  5. 5.Department of Non-communicable Disease PreventionShandong Province Centre for Disease Control and PreventionJinanChina
  6. 6.World Diabetes FoundationGentofteDenmark
  7. 7.R&DAstraZenecaMölndalSweden

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