Quality of Life Research

, Volume 23, Issue 5, pp 1523–1533 | Cite as

Factors associated with health-related quality of life among pulmonary tuberculosis patients in Manila, the Philippines

  • Shoichi MasumotoEmail author
  • Taro Yamamoto
  • Akihiro Ohkado
  • Shoji Yoshimatsu
  • Aurora G. Querri
  • Yasuhiko Kamiya



Health-related quality of life (HRQOL) among pulmonary tuberculosis (PTB) patients has not been investigated in the Philippines. This study aimed to describe HRQOL among PTB patients and to determine factors that are associated with HRQOL.


A cross-sectional survey was conducted at 10 public health centers and 2 non-government organization clinics in District I, Tondo, Manila. Face-to-face interviews using a structured questionnaire including Short Form-8, Duke-UNC Functional Social Support Questionnaire, and Medical Research Council (MRC) dyspnea scale were performed with 561 PTB patients from September to November 2012.


HRQOL among PTB patients was generally impaired. Factors associated with lower physical component summary were exposure to secondhand smoke (SHS) (P = 0.038), positive sputum smear result (P = 0.027), not working (P = 0.038), lower education level (P < 0.01), number of symptoms (P < 0.01), number of adverse drug reactions (ADRs) (P < 0.01), higher score on the MRC dyspnea scale (P < 0.01), and low perceived social support (P = 0.027). Lower body mass index (P = 0.016), non-SHS exposure (P = 0.033), number of symptoms (P < 0.01), number of ADRs (P < 0.01), low perceived social support (P < 0.01), and negative perception for waiting time in the clinic (P = 0.026) were identified to be factors significantly associated with lower mental component summary.


Socioeconomic status including SHS exposure and low perceived social support, in addition to clinical factors, may be associated with poor HRQOL. Further study would be needed to assess our findings.


Tuberculosis Health-related quality of life Secondhand smoke exposure Social support 



We appreciate the support of the technical and administrative staff of RJPI and cooperation from staff in each health center and NGOs. In addition, we wish to thank Dr. Pasquala Agujo, Chief of Division of TB Control; Dr. Romeo Cando, District Health Officer; and Ms. Gloria Inocencio, District Supervisor/NTP Nurse Coordinator; Dr. Armie Vianzon, NTP Medical Coordinator, for arranging and helping in the implementation of data collection. We also wish to thank all patients who participated in the study, and research assistants who conducted interview. This study was conducted as a research for master thesis of first author and funded by Graduated School of International Health Development, Nagasaki University.

Conflict of interest

None declared.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Shoichi Masumoto
    • 1
    Email author
  • Taro Yamamoto
    • 1
  • Akihiro Ohkado
    • 2
    • 3
  • Shoji Yoshimatsu
    • 2
    • 3
  • Aurora G. Querri
    • 2
  • Yasuhiko Kamiya
    • 1
  1. 1.Graduate School of International Health DevelopmentNagasaki UniversityNagasakiJapan
  2. 2.Research Institute of Tuberculosis/Japan Anti-Tuberculosis Association PhilippinesManilaThe Philippines
  3. 3.Research Institute of TuberculosisJapan Anti-Tuberculosis AssociationKiyoseJapan

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