Quality of Life Research

, Volume 22, Issue 1, pp 167–172 | Cite as

Validation of the Brazilian version of Chronic Liver Disease Questionnaire

  • Samantha Mucci
  • Vanessa de Albuquerque Citero
  • Adriano Miziara Gonzalez
  • Luciana Geocze
  • Stephan Geocze
  • Gaspar de Jesus Lopes Filho
  • Mario Alfredo De Marco
  • Edison Roberto Parise
  • Luiz Antonio Nogueira Martins
Brief Communication

Abstract

Purpose

The aim of this study was to validate the Chronic Liver Disease Questionnaire (CLDQ) for use in Brazilian population.

Method

A total of 200 patients with chronic liver disease and varying disease severity answered a socio-demographic questionnaire, t CLDQ, and the Medical Outcome Study Short Form 36 (SF-36). Patients returned in 1–15 days to answer CLDQ again. The Cronbach’s alpha of the total CLDQ score was 0.95 and fluctuated between 0.69 and 0.83 in its six domains.

Results

The intra-class correlation between total CLDQ scores in two evaluations was 0.97 and in all domains was >0.93. CLDQ was moderately correlated with the SF-36, 0.63 (total CLDQ vs. vitality, SF-36), 0.62 (CLDQ and mental health, SF-36), 0.62 (preoccupation, CLDQ, vs. General Health, SF-36), 0.59 (fatigue, CLDQ, vs. vitality, SF-36), 0.59 (activity, CLDQ, vs. vitality, SF-36), and 0.59 (fatigue, CLDQ, vs. mental health, SF-36). The highest scores were found in non-cirrhotic group. Child A patients had higher average scores than Child B and C groups in all domains, while patients with MELD <15 scored higher than patients with MELD ≥15.

Conclusion

CLDQ-BR was validated in Brazilian population and was appropriate for use in patients with liver disease of different etiologies and degrees of severity.

Keywords

Quality of life Chronic liver disease Validation CLDQ MELD 

References

  1. 1.
    Younossi, Z. M. (1998). Epidemiology of alcoholic liver disease. Clinical Liver Disease, 2(4), 661–671.CrossRefGoogle Scholar
  2. 2.
    [World Health Organization] Available from URL:http://www.who.int/mediacentre/factsheets/fs204/en/index.html accessed in [2003] (August, 2003).
  3. 3.
    Younossi, Z. M., Boparai, N., Kiwi, M., Price, L., & Guyatt, G. (2001). Health-related quality of life assessment in chronic liver disease: impact of type and severity of disease. American Journal of Gastroenterology, 96(7), 2199–2205.PubMedCrossRefGoogle Scholar
  4. 4.
    Bonkovsky, H. L., & Wooley, R. (1999). Reduction of health-related quality of life in HCV and improvement with interferon therapy. Hepatology, 29, 264–270.PubMedCrossRefGoogle Scholar
  5. 5.
    Sumskiene, J., Sumskas, L., Petrauskas, D., & Kupcinskas, L. (2006). Disease-specific health-related quality of life and its determinants in liver cirrhosis patients in Lithuania. World Journal of Gastroenterology, 12(48), 7792–7797.PubMedGoogle Scholar
  6. 6.
    Younossi, Z. M., McCormick, M., Boparai, N., Farquhar, L., Henderson, J. M., et al. (2000). The impact of liver transplantation on health-related quality of life. Liver Transplantation, 6, 779–783.PubMedCrossRefGoogle Scholar
  7. 7.
    O′Carrol, R. E., Couston, M., Cossar, J., Masterton, G., & Hayes, P. C. (2003). Psychological outcome and quality of life following liver transplantation: a prospective, national, single-center study. Liver Transplantation, 9, 712–720.CrossRefGoogle Scholar
  8. 8.
    Bravata, D. M., Olkin, I., Barnato, A. E., Keeffe, E. B., & Owens, D. K. (1999). Health-related quality of Life after liver transplantation: a meta-analysis. Liver Transplantation and Surgery, 5(4), 318–331.PubMedCrossRefGoogle Scholar
  9. 9.
    Younossi, Z. M., Guyatt, G., Kiwi, M., Boparai, N., & King, D. (1999). Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease. Gut, 45, 295–300.PubMedCrossRefGoogle Scholar
  10. 10.
    Häuser, W., Schnur, M., Steder-Neukamm, U., Muthny, F. A., & Grandt, D. (2004). Validation of the German version of the chronic liver disease questionnaire. European Journal of Gastroenterology and Hepatology, 16(6), 599–605.PubMedCrossRefGoogle Scholar
  11. 11.
    Sobhonslidsuk, A., Silpakit, C., Kongsakon, R., SatitpornKul, P., & Sripetch, C. (2004). Chronic liver disease questionnaire: translation and validation in Thai. World Journal of Gastroenterology, 10(13), 1954–1957.PubMedGoogle Scholar
  12. 12.
    Ferrer, M., Córdoba, J., Garin, O., Olivé, G., Flávia, M., Vargas, V., et al. (2006). Validity of the Spanish version of the Chronic Liver Disease Questionnaire (CLDQ) as a standard outcome for quality of life assessment. Liver Transplantation, 12(1), 95–104.PubMedCrossRefGoogle Scholar
  13. 13.
    Rucci, P., Taliani, G., Cirrincione, L., Alberti, A., Bartolozzi, D., Caporaso, N., et al. (2005). Validity and reliability of the Italian version of the Chronic Liver Disease Questionnaire (CLDQ-I) for the assessment of health related quality of life. Digestive and Liver Disease, 37(11), 850–860.PubMedCrossRefGoogle Scholar
  14. 14.
    Kollia, Z., Patelarou, E., Vivilaki, V., Kollia, E., Kefou, F., Elefsiniotis, I., et al. (2010). Translation and validation of the Greek chronic liver disease questionnaire. World Journal of Gastroenterology, 16(46), 5838–5844.PubMedCrossRefGoogle Scholar
  15. 15.
    Ray, I., Dutta, D., Basu, P., & De, B. K. (2010). Quality of life assessment of patients with chronic liver disease in eastern India using a Bengali translation chronic liver disease questionnaire. Indian Journal of Gastroenterology, 29(5), 187–195.PubMedCrossRefGoogle Scholar
  16. 16.
    Lam, E. T., Lam, C. L., Lai, C. L., Yuen, M. F., & Fong, D. Y. (2009). Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection. World Journal of Gastroenterology, 15(26), 3288–3297.PubMedCrossRefGoogle Scholar
  17. 17.
    Mahmoudi, H., Jafari, P., Alizadeh-Naini, M., Gholami, S., Malek-Hosseini, S.A., Ghaffaripour, S. (2011) Validity and reliability of Persian version of chronic liver disease questionnaire (CLDQ). Quality of Life Research 20(1), 1–7.Google Scholar
  18. 18.
    Ciconelli, R. M., Ferraz, M. B., Santos, W., Meinão, I., & Quaresma, M. R. (1999). Tradução para a língua portuguesa e validação do questionário genérico de avaliação de qualidade de vida SF-36. Revista Brasileira de Reumatologia, 39(3), 143–149.Google Scholar
  19. 19.
    Mucci, S., Citero, V. A., & Nogueira-Martins, L. A. (2005). Tradução e adaptação transcultural do instrumento de qualidade de vida específico para pacientes com hepatopatia crônica-Chronic Liver Disease Questionnaire (CLDQ). Revista Brasileira de Psiquiatria, 27, 60.Google Scholar
  20. 20.
    Child, C. G., & Turcotte, J. G. (1964). Surgery and portal hypertension: Major Problems. Clinical Surgery, 1, 1–85.Google Scholar
  21. 21.
    Wesner, R., Lake, J. R., Freeman, R. B., & Gish, R. G. (2006). Model for end-stage liver disease (MELD) exception guidelines. Liver Transplantation, 12(suppl 3), 85–87.CrossRefGoogle Scholar
  22. 22.
    Reichenheim, M. E., & Moraes, C. L. (2007). Operationalizing the cross-cultural adaptation of epidemiological measurement instruments. Revista de Saúde Pública, 41(4), 665–673.PubMedCrossRefGoogle Scholar
  23. 23.
    Freeman, R. B. (2005). MELD and the quality of life. Liver Transplantation, 11(2), 218–223.CrossRefGoogle Scholar
  24. 24.
    Wilson, J., & Cleary, P. (1995). Linking clinical variables with health related quality of life. JAMA, 273, 59–65.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Samantha Mucci
    • 1
  • Vanessa de Albuquerque Citero
    • 1
  • Adriano Miziara Gonzalez
    • 2
  • Luciana Geocze
    • 1
  • Stephan Geocze
    • 3
  • Gaspar de Jesus Lopes Filho
    • 2
  • Mario Alfredo De Marco
    • 1
  • Edison Roberto Parise
    • 3
  • Luiz Antonio Nogueira Martins
    • 1
  1. 1.Department of PsychiatryUniversidade Federal de São PauloSão PauloBrazil
  2. 2.Department of Surgical GastroenterologyUniversidade Federal de São PauloSão PauloBrazil
  3. 3.Department of Clinical GastroenterologyUniversidade Federal de São PauloSão PauloBrazil

Personalised recommendations