A PROMIS fatigue short form for use by individuals who have multiple sclerosis
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To derive from the Patient Reported Outcomes Measurement Information System (PROMIS) fatigue item bank, a short form for individuals with multiple sclerosis (MS), the PROMIS-FatigueMS.
A panel of 37 clinicians and 46 individuals with MS ranked the relevance of PROMIS fatigue items to persons with MS. Eight items were selected for the PROMIS-FatigueMS that maximized relevance rankings, content coverage, and item discrimination. The PROMIS-FatigueMS and an existing, 7-item PROMIS fatigue short form (PROMIS-FatigueSFv1.0) were administered to a new sample of 231 individuals with MS. Known groups and content validity were assessed.
Scores from the short forms were highly correlated (r = 0.92). Discriminant validity of the PROMIS-FatigueMS scores was supported in known groups comparisons. Scores of neither short form exhibited an advantage in quantitative analyses. The PROMIS-FatigueMS targeted more of the content included in participants’ responses to open-ended questions than did the PROMIS-FatigueSFv1.0.
The PROMIS-FatigueMS was derived to have content validity in MS samples. The validity of the measure was further supported by the ability of PROMIS-FatigueMS items to discriminate among groups expected to differ in levels of fatigue. We recommend its use in measuring the fatigue of individuals with MS.
KeywordsMultiple sclerosis Fatigue Outcomes assessment Psychometrics
- PROMIS-Fatigue SFv1.0
PROMIS 7-item fatigue short form, Version 1.0
Patient Reported Outcome Measurement Information System
Item response theory
University of Washington, Seattle
RI value based on participant rankings of 20 PROMIS items
RI value based on expert clinician rankings of 44 PROMIS items
Expanded Disability Status Scores
8-item Health Survey Short Form
- 1.National Multiple Sclerosis Society (2008). Clinical study measures: Mental health inventory. [cited June 27, 2008]; Available from: http://www.nationalmssociety.org/for-professionals/researchers/clinical-study-measures/mhi/index.Aspx. National Multiple Sclerosis Society.
- 12.Rothrock, N., Hays, R. D., Spritzer, K., Yount, S. E., Riley, W., & Cella, D. (2010). Relative to the general us population, chronic diseases are associated with poorer health-related quality of life as measured by the patient-reported outcomes measurement information system (PROMIS). Journal of Clinical Epidemiology, 63(11), 1195–1204.PubMedCrossRefGoogle Scholar
- 13.Riley, W. T., Rothrock, N., Bruce, B., Christodolou, C., Cook, K., Hahn, E. A., et al. (2010). Patient-reported outcomes measurement information system (PROMIS) domain names and definitions revisions: Further evaluation of content validity in irt-derived item banks. Quality of Life Research, 19(9), 1311–1321.PubMedCrossRefGoogle Scholar
- 14.Lai, J.-S., Cella, D., Choi, S., Junghaenel, D. U., Christodoulou, C., Gershon, R., et al. (in press). How item banks and their applications can influence measurement practice in rehabilitation medicine: A PROMIS fatigue item bank example. Archives of Physical Medicine and Rehabilitation.Google Scholar
- 15.U.S. Department of Health and Human Services Food and Drug Administration. (2009). http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm193282.pdf.
- 17.Amtmann, D., Cook, K. F., Johnson, K. L., Cella, D. (in press). The PROMIS initiative: Examples of applications in rehabilitation. Archives of Physical and Medical Rehabilitation.Google Scholar
- 21.Ware, J. E., Kosinski, M., Dewey, J. E., & Gandek, B. (2001). A manual for users of the sf-8 health survey. Lincoln, RI: Quality Metric Incorporated.Google Scholar
- 22.Flora, D. B., Thissen, D. (2002). User’s guide for IRTScore: Item response theory score approximation Software. Electronic Research Memorandum #2002-1. Chapel Hill, NC: University of North Carolina, L.L. Thurstone Psychometric Laboratory.Google Scholar
- 24.Given, B., Given, C. W., Sikorskii, A., Jeon, S., McCorkle, R., Champion, V., et al. (2008). Establishing mild, moderate, and severe scores for cancer-related symptoms: How consistent and clinically meaningful are interference-based severity cut-points? Journal of Pain and Symptom Management, 35(2), 126–135.PubMedCrossRefGoogle Scholar
- 25.Cella, D., Riley, W., Stone, A., Rothrock, N., Reeve, B., Yount, S., et al. (2010). The patient-reported outcomes measurement information system (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005–2008. Journal of Clinical Epidemiology, 63(11), 1179–1194.PubMedCrossRefGoogle Scholar