Quality of Life Research

, Volume 18, Issue 8, pp 961–969 | Cite as

Impact of demographic factors, medication and symptoms on disease-specific quality of life in inflammatory bowel disease

  • Johanna Haapamäki
  • Ulla Turunen
  • Risto P. Roine
  • Martti A. Färkkilä
  • Perttu E. T. Arkkila
Article

Abstract

Objectives

To investigate the relation of demographic factors, medication and symptoms to health-related quality of life in patients with inflammatory bowel disease, and to identify patients in need of special support.

Methods

A questionnaire packet comprising the Inflammatory Bowel Disease Questionnaire (IBDQ) and the European Federation of Crohn’s and Colitis Associations’ (EFCCA) Survey Questionnaire was sent to 3,852 adult members of the Crohn and Colitis Association of Finland. IBDQ was used for measuring health-related quality of life (HRQoL), and the EFCCA questionnaire gave information about demographics, symptoms and medication.

Results

Altogether 2,386 questionnaires (62%) were available for analysis. Patients reporting symptoms affecting leisure activities or work had significantly lower total IBDQ scores (indicating worse HRQoL) than patients with less disturbing symptoms. Satisfaction with current therapy, female gender and age affected the scores. Subjects who had undergone surgery scored lower than those who had not. Patients currently receiving corticosteroids and newly diagnosed patients had lower scores than other patients.

Conclusions

In everyday practice, paying attention to and reducing patients’ symptoms and their impact on daily life is important when aiming at improving HRQoL. Special attention should be given to patients who have undergone surgery, and to newly diagnosed patients.

Keywords

Crohn’s disease Health-related quality of life HRQoL IBD Inflammatory bowel disease Ulcerative colitis 

Abbreviations

CD

Crohn’s disease

EFCCA

European Federation of Crohn’s and Colitis Associations

HRQoL

Health-related quality of life

IBD

Inflammatory bowel disease

IBDQ

Inflammatory Bowel Disease Questionnaire

IC

Indeterminate/unspecified colitis

IPAA

Ileal pouch-anal anastomosis

UC

Ulcerative colitis

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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Johanna Haapamäki
    • 1
  • Ulla Turunen
    • 1
  • Risto P. Roine
    • 2
  • Martti A. Färkkilä
    • 1
  • Perttu E. T. Arkkila
    • 1
  1. 1.Department of Medicine, Division of GastroenterologyHelsinki University Central HospitalHUS, HelsinkiFinland
  2. 2.Group AdministrationHelsinki and Uusimaa Hospital DistrictHelsinkiFinland

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