Quality of Life Research

, Volume 18, Issue 6, pp 727–735 | Cite as

Reliability and validity of the SF-12v2 in the medical expenditure panel survey

  • Nancy C. Cheak-Zamora
  • Kathleen W. Wyrwich
  • Timothy D. McBride



Evaluate the reliability and validity of the Medical Outcomes Study Short-Form version 2 (SF-12v2) in the 2003–2004 Medical Expenditure Panel Survey (MEPS).

Research design

Data were collected in the self-administered mail-out questionnaire and face-to-face interviews of the MEPS (n = 20,661). Internal consistency and test–retest reliability and construct, discriminate, predictive and concurrent validity were tested. The EQ-5D, perceived health and mental health questions were used to test construct and discriminate validity. Self-reported work, physical and cognitive limits tested predictive validity and number of chronic conditions assessed concurrent validity.


Both Mental Component Summary Scores (MCS) and Physical Component Summary Scores (PCS) were shown to have high internal consistency reliability (α > .80). PCS showed high test–retest reliability (ICC = .78) while MCS demonstrated moderate reliability (ICC = .60). PCS had high convergent validity for EQ-5D items (except self-care) and physical health status (r > .56). MCS demonstrated moderate convergent validity on EQ-5D and mental health items (r > .38). PCS distinguish between groups with different physical and work limitations. Similarly, MCS distinguished between groups with and without cognitive limitations. The MCS and PCS showed perfect dose response when variations in scores were examined by participant’s chronic condition status.


Both component scores showed adequate reliability and validity with the 2003–2004 MEPS and should be suitable for use in a variety of proposes within this database.


SF-12 MEPS Medical expenditure panel survey Validity Reliability 



Agency for healthcare research and quality


Analysis of variance


Brief pain inventory modified for patients with diabetic peripheral neuropathy


Diagnostic and statistical manual of mental disorders 4th


EuroQoL- 5 dimension


Intraclass correlation coefficient


Medical expenditure panel survey


Medical expenditure panel survey household component


Mental component summary score


National center of health statistics


Physical component summary score


Patient generated index


Self-administered questionnaire


Medical outcomes study 12-item short-form version 1


Medical outcomes study 12-item short-form version 2


Medical outcomes study 36-item short form


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Nancy C. Cheak-Zamora
    • 1
  • Kathleen W. Wyrwich
    • 2
  • Timothy D. McBride
    • 3
  1. 1.School of Public HealthSaint Louis UniversitySt. LouisUSA
  2. 2.United BioSource CorporationBethesdaUSA
  3. 3.George Warren Brown School of Social WorkWashington UniversitySt. LouisUSA

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