Quality of Life Research

, Volume 16, Issue 10, pp 1595–1603

The association between body mass index and health-related quality of life: data from CaMos, a stratified population study

  • Wilma M. Hopman
  • Claudie Berger
  • Lawrence Joseph
  • Susan I. Barr
  • Yongjun Gao
  • Jerilynn C. Prior
  • Suzette Poliquin
  • Tanveer Towheed
  • Tassos Anastassiades
  • CaMos Research Group



Deviation from normal weight is associated with health risks, but less is known about the association between weight and health-related quality of life (HRQOL). We investigated this in the context of a population-based study, using a standard five-category weight classification system based on body mass index (BMI).


The Canadian Multicentre Osteoporosis Study is a randomly selected sample of men and women over 25 years of age from nine centres across Canada. Data were obtained by interview, and height and weight were measured and used to calculate BMI. HRQOL was measured using the SF-36. Multivariable linear regression was used to identify the association between BMI category and SF-36 scores after controlling for potential confounders.


Complete data were available for 6302 women and 2792 men. Mean BMI for every age and gender group exceeded healthy weight guidelines. For women, being underweight, overweight or obese was associated with poorer HRQOL in most SF-36 outcomes while for men, this was associated with poorer HRQOL in some domains and with higher HRQOL in others.


A significant proportion of the population may be putting their health at risk due to excess weight, which may have a substantial negative effect on HRQOL, particularly in women. This underscores the need for continued public health efforts aimed at combating overweight and obesity.


BMI Body mass index Epidemiology SF-36 



Health-related quality of life


Medical Outcomes Trust 36-item Health Survey


Body mass index


Canadian Multicentre Osteoporosis Study


Physical component summary of the SF-36


Mental component summary of the SF-36


Dual-energy X-ray absorptiometry


Bone mineral density


Confidence interval


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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • Wilma M. Hopman
    • 1
    • 2
  • Claudie Berger
    • 3
  • Lawrence Joseph
    • 4
  • Susan I. Barr
    • 5
  • Yongjun Gao
    • 3
  • Jerilynn C. Prior
    • 6
  • Suzette Poliquin
    • 7
  • Tanveer Towheed
    • 2
    • 8
  • Tassos Anastassiades
    • 8
  • CaMos Research Group
  1. 1.Clinical Research CentreKingston General HospitalKingstonCanada
  2. 2.Department of Community Health and EpidemiologyQueen’s UniversityKingstonCanada
  3. 3.CaMos Methods CentreMcGill UniversityMontrealCanada
  4. 4.Department of Epidemiology and BiostatisticsMcGill UniversityMontrealCanada
  5. 5.Human NutritionUniversity of British ColumbiaVancouverCanada
  6. 6.Division of Endocrinology, Department of MedicineUniversity of British Columbia VancouverCanada
  7. 7.CaMos National Coordinating CentreMcGill UniversityMontrealCanada
  8. 8.Division of Rheumatology, Department of MedicineQueen’s UniversityKingstonCanada

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