Quality of Life Research

, Volume 15, Issue 6, pp 1069–1078 | Cite as

Responsiveness of the coronary revascularisation outcome questionnaire compared with the SF-36 and Seattle Angina Questionnaire



We describe a comparison of the responsiveness of three validated instruments when used with patients undergoing coronary bypass surgery (CABG) and angioplasty (PTCA). Patients were randomly selected to receive the Coronary Revascularisation Outcome Questionnaire (CROQ), and either the Seattle Angina Questionnaire (SAQ), or the SF-36 before and 3 months after coronary revascularisation. At total of 199 patients (127 CABG, 72 PTCA) completed the CROQ; 55/72 CABG and 34/38 PTCA patients also completed the SAQ or SF-36, respectively. Effect sizes and standardised response means were calculated as change over the 3-month period for scales measuring similar constructs on each instrument. We used bootstrap estimation to derive 95% confidence intervals for differences in the responsiveness indices. For CABG, the CROQ demonstrated significantly greater change in psychosocial functioning than the SF-36, but less than the SAQ. For PTCA, the CROQ showed greater change for symptoms than the SAQ, but the SAQ was more responsive in terms of physical functioning; and the CROQ showed significantly greater change than the SF-36 for psychosocial functioning. There were no other significant differences between similar scales on the three instruments. In conclusion, the CROQ was as responsive as the disease-specific SAQ and more responsive than the generic SF-36.


Angioplasty Coronary artery bypass grafting Quality of life Questionnaire Responsiveness 



coronary artery bypass grafting


Coronary Revascularisation Outcome Questionnaire


effect size


SF-36 Mental Component Summary score


SF-36 Physical Component Summary score


percutaneous transluminal coronary angioplasty, now also known as percutaneous coronary intervention (PCI)


Seattle Angina Questionnaire


MOS 36-Item Short-Form Health Survey


standardised response mean


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Copyright information

© Springer 2006

Authors and Affiliations

  1. 1.Health Services Research UnitLondon School of Hygiene & Tropical MedicineLondonUK
  2. 2.BMJ Editorial OfficeLondonUK

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