Advertisement

Quality of Life Research

, Volume 14, Issue 1, pp 11–19 | Cite as

Subjective quality of life in patients with chronic fatigue syndrome

  • A. Rakib
  • P. D. White
  • A. J. Pinching
  • B. Hedge
  • N. Newbery
  • W. K. Fakhoury
  • S. PriebeEmail author
Article

Abstract

The aim of this study was to (1) assess Subjective Quality of Life (SQOL) of patients with Chronic Fatigue Syndrome (CFS) using a generic concept and to compare the findings with those in groups with mental disorders and healthy subjects, and (2) investigate whether and, if so, to what extent socio-demographic and clinical variables predict SQOL in CFS patients. Seventy-three patients diagnosed with CFS were randomly selected and interviewed from two specialised clinics. CFS was diagnosed using the Oxford Criteria. SQOL was assessed on the Manchester Short Assessment of Quality of Life (MANSA) and Health-Related Quality of Life (HRQOL) on the Medical Outcome Study Short-Form 36 (MOS) SF-36. A battery of mood and symptom questionnaires, including the Symptom Checklist Questionnaire (SCL-90-R), was administered to assess various aspects of symptomatology as potential predictor variables. Multiple regression analyses were conducted to identify predictors of SQOL. Overall, SQOL was low in CFS patients and less favourable than in groups with mental disorders and healthy subjects. Satisfaction was particularly low with life as a whole, leisure activities and financial situation. Whilst SQOL was only moderately correlated with HRQOL, the SCL-90-R score, especially SCL-90-R Depression scale score, was the best predictor of SQOL explaining 35% of the variance. HRQOL and generic SQOL appear distinct despite some overlap. The findings underline that SQOL is significantly disrupted in CFS patients. Depressive symptoms are statistically the strongest ‘predictor’ of SQOL, although the direction of the relationship is not established. These data suggest that treatment of depression associated with CFS, regardless of causation, could help to improve SQOL in CFS patients.

Keywords

Chronic fatigue syndrome Health related quality of life Quality of life Subjective quality of life 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Fukuda, K, Straus, SE, Hickie, I, Sharpe, MC, Dobbins, JG, Komaroff, A 1994The chronic fatigue syndrome: A comprehensive approach to its definition and study.International Chronic Fatigue Syndrome Study Group. Ann Intern Med121953959Google Scholar
  2. Sharpe, MC, Archard, LE, Banatvala, J 1991A report–chronic fatigue syndrome.J R Soc Med84118121PubMedGoogle Scholar
  3. Komaroff, A. 1993Clinical presentation of chronic fatigue syndromeStraus, SKleinman, A eds. Chronic Fatigue SyndromeJohn WileyChichesterGoogle Scholar
  4. Short, K, McCabe, M, Tooley, G 2002Cognitive functioning in chronic fatigue syndrome and the role of depression, anxiety and fatigue.J Psychosom Res52475483CrossRefPubMedGoogle Scholar
  5. Lehman, AM, Lehman, DR, Hemphill, KJ, Mandel, DR, Cooper, LM 2002Illness experience, depression and anxiety in chronic fatigue syndrome.J Psychosom Res52461465CrossRefPubMedGoogle Scholar
  6. Schweitzer, R, Kelly, B, Foran, A, Terry, D, Whitting, J 1995Quality of life in chronic fatigue syndrome.Social Sci Med4113671372CrossRefGoogle Scholar
  7. Metzger, FA, Denney, DR 2002Perception of cognitive performance in patients with chronic fatigue syndrome.Ann Behav Med24106112CrossRefPubMedGoogle Scholar
  8. Whiting, P, Bagnall, A, Sowden, A, Cornell, J, Mulrow, C, Ramirez, G 2001Interventions for the treatment and management of chronic fatigue syndrome: A systematic reviewJAMA28613601368CrossRefPubMedGoogle Scholar
  9. Anderson, JS, Ferrans, CE 1997The quality of life of persons with chronic fatigue syndrome.JNMD185359367CrossRefGoogle Scholar
  10. Hardt, J, Buchwald, D, Wilks, D, Sharpe, M, Nix, WA, Egle, UT 2001Health-related quality of life in patients with chronic fatigue syndrome: An international study.J Psychosom Res51431434CrossRefPubMedGoogle Scholar
  11. Herrell, R, Goldberg, J, Hartman, S, Belcourt, M, Schmaling, K, Buchwald, D 2002Chronic fatigue and chronic fatigue syndrome: A co-twin control study of functional statusQual Life Res11463471CrossRefPubMedGoogle Scholar
  12. Lee, S, Yu, H, Wing, Y,  et al. 2000Psychiatric morbidity and illness experience of primary care patients with chronic fatigue in Hong KongAm J Psychiat157380384CrossRefPubMedGoogle Scholar
  13. White, PD, Pinching, AJ, Rakib, A, Castle, M, Hedge, B, Priebe, S 2002A comparison of patients with chronic fatigue syndrome attending separate fatigue clinics based in immunology and psychiatry.J Roy Soc Med95440444CrossRefGoogle Scholar
  14. Chalder, T, Berelowitz, G, Pawlikowska, T,  et al. 1993Development of a Fatigue Scale.J Psychosomatic Res37147153CrossRefGoogle Scholar
  15. White, PD, Grover, SA, Kangro, HO 1995The validity and reliability of the fatigue syndrome that follows glandular feverPsychol Med45712Google Scholar
  16. Priebe, S, Huxley, P, Knight, S, Evans, S 1999Application and results of the Manchester short assessment of quality of life (MANSA).Int J Social Psychiat45712Google Scholar
  17. Lehman, AF, Ward, NC, Linn, LL 1982Chronic mental patients: Quality of life issue.Am J Psychiat13912711276PubMedGoogle Scholar
  18. Lehman, AF, Possidente, S, Hawker, F 1986The quality of life of chronic patients in a state hospital and in community residences.Hospital Commun Psychiat37901907Google Scholar
  19. Oliver, JPJ 1991-1992The social care directive: Development of a quality of life profile for use in community services for the mentally illSocial Work Social Serv Rev3545Google Scholar
  20. Garrat, AM, Ruta, DA, Abdalla, MI, Buckingham, JK, Russel, IT 1993The SF-36 health survey questionnaire: An outcome measure suitable for routine use within the NHS?Br Med J30614401444Google Scholar
  21. Peveler, RC, Fairburn, GC 1990Measurement of neurotic symptoms by self-report questionnaire: Validity of the SCL-90R.Psychol Med20873879PubMedGoogle Scholar
  22. Spielberger, CD, Gorsuch, RL, Lushene, R, Vagg, PR, Jacobs, GA 1968Self Evaluation Questionnaire; STAI Form.Consulting Psychologists PressPalo Alto, CaliforniaGoogle Scholar
  23. Beck, AT, Weismann, A, Lester, D, Trexler, L 1974The measurement of pessimism: The hopelessness scale.J Consult Clin Psychol42861866PubMedGoogle Scholar
  24. Lucock, MP, Morley, S 1996The health anxiety questionnaire.Br J Health Psychol1137150Google Scholar
  25. Wittenborn, JR, Buhler, R 1979Somatic discomfort among depressed womenArch Gen Psychiat36465471PubMedGoogle Scholar
  26. Buchwald, D, Pearlman, T, Umali, J, Schmaling, K, Katon, W 1996Functional status in patients with CFS, other fatiguing illnesses and healthy individuals.Am J Med101364370CrossRefPubMedGoogle Scholar
  27. Komaroff, AL, Fagioli, LR, Doolittle, TH 1996Health status in patients with CFS and in general population and disease comparison groups.Am J Med101281290CrossRefPubMedGoogle Scholar
  28. Priebe, S, Roder-Wanner, UU, Kaiser, W 2000Quality of life in first-admitted schizophrenia patients: A follow-up study.Psychol Med30225230CrossRefPubMedGoogle Scholar
  29. Rudolf, H, Priebe, S 1999Similarities and differences in subjective quality of life of alcoholic women (in German)Psychiatrische Praxis26116126PubMedGoogle Scholar
  30. Rudolf, H, Priebe, S 1999Subjective quality of life in female in-patients with depression: A longitudinal study.Int J Soc Psychiat45238246PubMedGoogle Scholar
  31. Priebe, S, Gruyters, T, Heinze, M, Hoffmann, C, Jakel, A 1995Subjective evaluation criteria in psychiatric care–methods for assessment in research and routine care.Psychiatrische Praxis22140144PubMedGoogle Scholar
  32. Priebe, S 1999Research in quality of life in mental health care: Aims and strategiesPriebe, SOliver, JPJKaiser, W eds. Quality of life and Mental Health CareWrightson Biomedical PublishingPetersfield139154Google Scholar
  33. Kaiser, W, Priebe, S, Barr, W,  et al. 1997Profiles of subjective quality of life in schizophrenic in- and out-patient samples.Psychiat Res66153166CrossRefGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • A. Rakib
    • 1
  • P. D. White
    • 2
  • A. J. Pinching
    • 2
  • B. Hedge
    • 2
  • N. Newbery
    • 2
  • W. K. Fakhoury
    • 1
  • S. Priebe
    • 1
    Email author
  1. 1.The Unit for Social and Community Psychiatry, Barts and the LondonQueen Mary’s School of Medicine and Dentistry, Newham Centre for Mental HealthLondonUK
  2. 2.The Departments of Psychiatry and Immunology, Barts and the LondonQueen Mary’s School of Medicine and DentistryLondonUK

Personalised recommendations