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Plant Foods for Human Nutrition

, Volume 66, Issue 4, pp 401–407 | Cite as

Effects of Feeding Potato Pulp on Cholesterol Metabolism and Its Association with Cecal Conditions in Rats

  • Naoto HashimotoEmail author
  • Yumi Nakamura
  • Takahiro Noda
  • Kyu-Ho Han
  • Michihiro Fukushima
ORIGINAL PAPER

Abstract

To clarify the functional properties of potato pulp (PP), a waste product resulting from extraction of starch from potatoes, we examined the effects of PP on cholesterol metabolism and cecal conditions in rats. Plasma total cholesterol (T-Chol) levels were lower in rats fed a PP-supplemented diet for four weeks than in those fed a control diet. Cecal pH was lowered due to an increase in the levels of cecal total short-chain fatty acids, especially butyrate, in the PP group compared to the control group. Furthermore, animals fed with the PP-supplemented diet showed increased cecal ratios of Lactobacillus and Clostridia and decreased cecal ratios of Bacteroides and Gammaproteobacteria with slightly negative and positive correlations with plasma T-Chol levels, respectively. In conclusion, ingestion of PP for four weeks is likely to improve both cecal conditions and cholesterol metabolism, suggesting that PP has prebiotic effects.

Keywords

Cholesterol Intestinal bacteria Potato pulp Prebiotic effects Rat Short-chain fatty acids 

Abbreviations

BA

Bile acid

Chol

Cholesterol

CYP7A1

Cytochrome P450 family 7, subfamily A, polypeptide 1

DF

Dietary fiber

GAPDH

Glyceraldehyd-3-phosphate dehydrogenase

HDL

High-density lipoprotein

HMG-CoA

Hydroxymethylglutaryl-coenzyme A

O-Chol

Other cholesterol than high-density lipoprotein cholesterol

PP

Potato pulp

RT-PCR

Reverse transcriptase-polymerase chain reaction

SCFA

Short-chain fatty acid

TBA

Total bile acid

T-Chol

Total cholesterol

T-RFLP

Terminal restriction fragment length polymorphism

Notes

Acknowledgments

This work was supported in part by grants-in-aid from The Ministry of Agriculture, Forestry and Fisheries of Japan. We thank Dr. Benli for providing fragment data of T-RFLP and Minako Saito for her skillful assistance.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Naoto Hashimoto
    • 1
    • 2
    Email author
  • Yumi Nakamura
    • 3
  • Takahiro Noda
    • 2
  • Kyu-Ho Han
    • 3
  • Michihiro Fukushima
    • 3
  1. 1.Koshi Headquarters, National Agricultural Research Center for Kyushu Okinawa RegionKumamotoJapan
  2. 2.Memuro Upland Farming Research Station, National Agricultural Research Center for Hokkaido RegionMemuroJapan
  3. 3.Department of Animal ScienceObihiro University of Agriculture and Veterinary medicineObihiroJapan

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