Prevention Science

, Volume 19, Issue 3, pp 328–336 | Cite as

The Ultimate Goal of Prevention and the Larger Context for Translation

  • Anthony Biglan


Type II translational research tends to emphasize getting evidence-based programs implemented in real world settings. To fully realize the aspirations of prevention scientists, we need a broader strategy for translating knowledge about human wellbeing into population-wide improvements in wellbeing. Far-reaching changes must occur in policies and cultural practices that affect the quality of family, school, workplace, and community environments. This paper describes a broad cultural movement, not unlike the tobacco control movement, that can make nurturing environments a fundamental priority of public policy and daily life, thereby enhancing human wellbeing far beyond anything achieved thus far.


Improved wellbeing Translational research Policy change Nurturing environments Cultural evolution 



The National Institute on Alcohol Abuse and Alcoholism (1R01AA021726) and the National Institute of Child Health and Development (1R01HD060922) provided financial support for the author during his work on this manuscript. The content is solely the responsibility of the author and does not necessarily represent the official views of NIAAA, NICHD, or the National Institutes of Health. The author thanks Christine Cody for her editorial assistance.

Compliance with Ethical Standards

Conflict of Interest

The author declares that he has no conflict of interest.

Research Involving Human Participants and/or Animals

This article has no methods section and provides no other information on studies with human participants or animals performed by the author.


  1. Abramowitz, M., & Albrecht, J. (2013). The community loss index: A new social indicator. Social Service Review, 87, 677–724.CrossRefGoogle Scholar
  2. Abroms, L. C., & Maibach, E. W. (2008). The effectiveness of mass communication to change public behavior. Annual Review of Public Health, 29, 219–234.CrossRefPubMedGoogle Scholar
  3. Arthur, M. W., Hawkins, J. D., Pollard, J. A., Catalano, R. F., & Baglioni, A. J., Jr. (2002). Measuring risk and protective factors for substance use, delinquency, and other adolescent problem behaviors. Evaluation Review, 26, 355–381.CrossRefGoogle Scholar
  4. Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Bradley, R. H., & Bradley, R. H. (2005). Those who have, receive: The Matthew effect in early childhood intervention in the home environment. Review of Educational Research, 75, 1–26.CrossRefGoogle Scholar
  5. Baldwin, S. A., Murray, D. M., & Shadish, W. R. (2005). Empirically supported treatments or type I errors? Problems with the analysis of data from group-administered treatments. Journal of Consulting and Clinical Psychology, 73, 924–935.CrossRefPubMedGoogle Scholar
  6. Baron, J. (2007). Making policy work: The lesson from medicine (commentary). Education Week. Online at
  7. Biglan, A. (2004). Direct written testimony in the case of the U.S.A. vs. Phillip Morris et al. Washington, DC: U.S. Department of Justice.Google Scholar
  8. Biglan, A. (2011). Corporate externalities: A challenge to the further success of prevention science. Prevention Science, 12, 1–11.CrossRefPubMedPubMedCentralGoogle Scholar
  9. Biglan, A. (2015a). The nurture effect: How the science of human behavior can improve our lives and our world. Oakland, CA: New Harbinger.Google Scholar
  10. Biglan, A. (2015b). Evolving a more nurturing capitalism: A new Powell memo. This View of Life. Available at
  11. Biglan, A., & Cody, C. (2013). Integrating the human sciences to evolve effective policies. Journal of Economic Behavior & Organization, 90S, S152–S162.CrossRefGoogle Scholar
  12. Biglan, A., Ary, D., & Wagenaar, A. C. (2000a). The value of interrupted time-series experiments for community intervention research. Prevention Science, 1, 31–49.CrossRefPubMedPubMedCentralGoogle Scholar
  13. Biglan, A., Ary, D. V., Smolkowski, K., Duncan, T. E., & Black, C. (2000b). A randomized control trial of a community intervention to prevent adolescent tobacco use. Tobacco Control, 9, 24–32.CrossRefPubMedPubMedCentralGoogle Scholar
  14. Biglan, A., Brennan, P. A., Foster, S. L., & Holder, H. D. (2004). Helping adolescents at risk: Prevention of multiple problem behaviors. New York: Guilford.Google Scholar
  15. Biglan, A., & Embry, D. D. (2013). A framework for intentional cultural change. Journal of Contextual Behavioral Science, 2, 95–104.CrossRefGoogle Scholar
  16. Biglan, A., Flay, B. R., Embry, D. D., & Sandler, I. (2012). Nurturing environments and the next generation of prevention research and practice. American Psychologist, 67, 257–271.CrossRefPubMedPubMedCentralGoogle Scholar
  17. Biglan, A., Severson, H., Ary, D. V., Faller, C., Gallison, C., Thompson, R., et al. (1987). Do smoking prevention programs really work? Attrition and the internal and external validity of an evaluation of a refusal skills training program. Journal of Behavioral Medicine, 10, 159–171.CrossRefPubMedGoogle Scholar
  18. Biglan, A., & Taylor, T. K. (2000). Why have we been more successful in reducing tobacco use than violent crime? American Journal of Community Psychology, 28, 269–302.CrossRefPubMedGoogle Scholar
  19. Bracht, N. (1999). Health promotion at the community level. Thousand Oaks: Sage.Google Scholar
  20. Cardosos, G. (2005). Societies in transition to the network society. In M. Castells & G. Cardoso (Eds.), The network society: From knowledge to policy (pp. 23–70). Washington, DC: Johns Hopkins Center for Transatlantic Relations.Google Scholar
  21. Centers for Disease Control and Prevention. (2012). Current cigarette smoking among adults-United States, 2011. Morbidity and Mortality Weekly Report, 61, 889–894.Google Scholar
  22. Conger, R. D., Patterson, G. R., & Ge, X. (1995). It takes two to replicate: A mediational model for the impact of parents’ stress on adolescent adjustment. Child Development, 66, 80–97.CrossRefPubMedGoogle Scholar
  23. D’Agostino, R. B., Massaro, J. M., & Sullivan, L. M. (2003). Non‐inferiority trials: design concepts and issues–the encounters of academic consultants in statistics. Statistics in Medicine, 22, 169–186.CrossRefPubMedGoogle Scholar
  24. Dishion, T. J., & Snyder, J. (2004). An introduction to the special issue on advances in process and dynamic system analysis of social interaction and the development of antisocial behavior. Journal of Abnormal Child Psychology, 32, 575–578.CrossRefPubMedGoogle Scholar
  25. Eamon, M. K. (2001). The effects of poverty on children’s socioemotional development: An ecological systems analysis. Social Work, 46, 256–266.CrossRefPubMedGoogle Scholar
  26. Elder, G. H., Van Nguyen, T., & Caspi, A. (1995). Linking family hardship to children’s lives. Child Development, 56, 361–375.CrossRefGoogle Scholar
  27. Embry, D. D., & Biglan, A. (2008). Evidence-based kernels: Fundamental units of behavioral influence. Clinical Child and Family Psychology Review, 11, 75–113.CrossRefPubMedPubMedCentralGoogle Scholar
  28. Feinberg, M. E., Jones, D., Greenberg, M. T., Osgood, D. W., & Bontempo, D. (2010). Effects of the communities that care model in Pennsylvania on change in adolescent risk and problem behaviors. Prevention Science, 11, 163–171.CrossRefPubMedPubMedCentralGoogle Scholar
  29. Fisher, P. A., & Chamberlain, P. (2000). Multidimensional treatment foster care a program for intensive parenting, family support, and skill building. Journal of Emotional and Behavioral Disorders, 8, 155–164.CrossRefGoogle Scholar
  30. Flay, B. R. (1986). Efficacy and effectiveness trials (and other phases of research) in the development of health promotion programs. Preventive Medicine, 15, 451–474.CrossRefPubMedGoogle Scholar
  31. Flay, B. R., Biglan, A., Boruch, R. F., Castro, F. G., Gottfredson, D., Kellam, S., et al. (2005). Standards of evidence: criteria for efficacy, effectiveness, and dissemination. Prevention Science, 6, 151–175.CrossRefPubMedGoogle Scholar
  32. Forgatch, M. S., Patterson, G. R., & DeGarmo, D. S. (2005). Evaluating fidelity: Predictive validity for a measure of competent adherence to the Oregon model of parent management training. Behavior Therapy, 36, 3–13.CrossRefPubMedPubMedCentralGoogle Scholar
  33. Galobardes, B., Lynch, J. W., & Smith, G. D. (2004). Childhood socioeconomic circumstances and cause-specific mortality in adulthood: Systematic review and interpretation. Epidemiologic Reviews, 26, 7–21.CrossRefPubMedGoogle Scholar
  34. Glasgow, R. E., & Steiner, J. F. (2012). Comparative effectiveness research to accelerate translation: Recommendations for an emerging field of science. In R. C. Brownson, G. Colditz, & E. Proctor (Eds.), Dissemination and implementation research in health: Translating science and practice (pp. 72–93). New York: Oxford University Press.CrossRefGoogle Scholar
  35. Gottfredson, D. C, Cook, T. D., Gardner, F. E. M., Gorman-Smith, D., Howe, G. W., Sandler, I. N., Zafft, K. M. (2015). Standards of evidence for efficacy, effectiveness, and scale-up research in prevention science: Next generation. Prevention Science.Google Scholar
  36. Gould, E., & Wething, H. (2012). US poverty rates higher, safety net weaker than in peer countries. Economic Policy Institute Issue brief #339. Available online at
  37. Greene, C. J., Morland, L. A., Durkalski, V. L., & Frueh, B. C. (2008). Noninferiority and equivalence designs: Issues and implications for mental health research. Journal of Traumatic Stress, 21, 433–439.CrossRefPubMedPubMedCentralGoogle Scholar
  38. Hacker, J. S., & Pierson, P. (2010). Winner-take-all politics: Public policy, political organization, and the precipitous rise of top incomes in the U.S. Politics & Society, 38, 152–204.CrossRefGoogle Scholar
  39. Hacker, J. S., Pierson, P., & Moyers, B. D. (2012). Winner-take-all politics. New York: Simon & Schuster.Google Scholar
  40. Hawkins, J., Oesterle, S., Brown, E. C., Abbott, R. D., & Catalano, R. F. (2014). Youth problem behaviors 8 years after implementing the communities that care prevention system: A community-randomized trial. JAMA Pediatrics, 168, 122–129.CrossRefPubMedPubMedCentralGoogle Scholar
  41. Henggeler, S. W., Clingempeel, W. G., Brondino, M. J., & Pickrel, S. G. (2002). Four-year follow-up of multisystemic therapy with substance-abusing and substance-dependent juvenile offenders. Journal of the American Academy of Child & Adolescent Psychiatry, 41, 868–874.CrossRefGoogle Scholar
  42. Institute of Medicine. (2007). Ending the tobacco problem: A blueprint for the nation. Washington, DC: The National Academies Press.Google Scholar
  43. Johnson, S. (2006). The ghost map. New York: Riverhead Books.Google Scholar
  44. Jonkman, H. B., Haggerty, K. P., Steketee, M., Fagan, A., Hanson, K., & Hawkins, J. D. (2009). Communities that care, core elements and context: research of implementation in two countries. Social Development Issues, 30, 42–57.PubMedPubMedCentralGoogle Scholar
  45. Jordá, V., & Sarabia, J. M. (2015). International convergence in well-being indicators. Social Indicators Research, 120, 1–27Google Scholar
  46. Kellam, S. G., Koretz, D., & Mościcki, E. K. (1999). Core elements of developmental epidemiologically based prevention research. American Journal of Community Psychology, 27, 463–482.CrossRefPubMedGoogle Scholar
  47. Kitzman, H., Olds, D. L., Sidora, K., Henderson Jr, C. R., Hanks, C., Cole, R., ... & Glazner, J. (2000). Enduring effects of nurse home visitation on maternal life course: a 3-year follow-up of a randomized trial. Journal of the American Medical Association, 283, 1983–1989.Google Scholar
  48. Komro, K. A., Biglan, A., Flay, B. R., & Promise Neighborhoods Research Consortium. (2011). Creating nurturing environments: A science-based framework for promoting child health and development within high-poverty neighborhoods. Clinical Child and Family Psychology Review, 14, 111–134.CrossRefPubMedPubMedCentralGoogle Scholar
  49. Komro, K. A., Tobler, A. L., Delisle, A. L., Ryan, J. O., & Wagenaar, A. C. (2013). Beyond the clinic: Improving child health through evidence-based community development. BMC Pediatrics, 13, 172. Available at
  50. Komro, K., O’Mara, R. J., & Wagenaar, A. (April 10, 2012). Mechanisms of legal effect: Perspectives from public health. Public Health Law Research Methods Monograph Series. Available at SSRN:
  51. Lexchin, J., Bero, L. A., Djulbegovic, B., & Clark, O. (2003). Pharmaceutical industry sponsorship and research outcome and quality: Systematic review. British Medical Journal, 326, 1167–1170.CrossRefPubMedPubMedCentralGoogle Scholar
  52. Lichtenstein, E., Zhu, S. H., & Tedeschi, G. J. (2010). Smoking cessation quitlines: An under-recognized intervention success story. American Psychologist, 65, 252–261.CrossRefPubMedPubMedCentralGoogle Scholar
  53. McElwee, S. (2013 November). GOP is an anti-science party of nuts (sorry, Atlantic). Salon.
  54. McLean, B., & Nocera, J. (2010). All the devils are here: Unmasking the men who bankrupted the world. London: Penguin UK.Google Scholar
  55. McLoyd, V. C. (1998). Socioeconomic disadvantage and child development. American Psychologist, 53, 185–204.CrossRefPubMedGoogle Scholar
  56. Mrazek, P., Biglan, A., & Hawkins, J.D. (2004). Community-monitoring systems: Tracking and improving the well-being of America’s children and adolescents. Falls Church, VA: SPR at
  57. Murray, D. M. (1998). Design and analysis of group-randomized trials. New York: Oxford University Press.Google Scholar
  58. National Cancer Institute (2008). The role of the media in promoting and reducing tobacco use. Tobacco Control Monograph No. 19. Bethesda, MD: USDHHS.Google Scholar
  59. National Research Council and Institute of Medicine. (2009). Preventing mental, emotional, and behavioral disorders among young people: Progress and possibilities. Washington, DC: The National Academies Press.Google Scholar
  60. Nichols, M. P., & Schwartz, R. C. (1998). Family therapy: Concepts and methods. New York: Allyn & Bacon.Google Scholar
  61. Olds, D. L. (2006). The nurse–family partnership: An evidence‐based preventive intervention. Infant Mental Health Journal, 27, 5–25.CrossRefPubMedGoogle Scholar
  62. Olds, D. L., Eckenrode, J., Henderson, C. R., Kitzman, H., Powers, J., Cole, R., & Luckey, D. (1997). Long-term effects of home visitation on maternal life course and child abuse and neglect: Fifteen-year follow-up of a randomized trial. Journal of the American Medical Association, 278, 637–643.Google Scholar
  63. Patterson, G. R., Forgatch, M. S., & DeGarmo, D. S. (2010). Cascading effects following intervention. Development and Psychopathology, 22, 949–970.Google Scholar
  64. Petrosino, A., & Soydan, H. (2005). The impact of program developers as evaluators on criminal recidivism: Results from meta-analyses of experimental and quasi-experimental research. Journal of Experimental Criminology, 1, 435–450.CrossRefGoogle Scholar
  65. Reeves, A., Stuckler, D., McKee, M., Gunnell, D., Chang, S. S., & Basu, S. (2012). Increase in state suicide rates in the USA during economic recession. The Lancet, 380, 1813–1814.CrossRefGoogle Scholar
  66. Reiss, F. (2013). Socioeconomic inequalities and mental health problems in children and adolescents: A systematic review. Social Science & Medicine, 90, 24–31.CrossRefGoogle Scholar
  67. Sanders, M. R. (1999). Triple P-positive parenting program: Towards an empirically validated multilevel parenting and family support strategy for the prevention of behavior and emotional problems in children. Clinical Child and Family Psychology Review, 2, 71–90.CrossRefPubMedGoogle Scholar
  68. Shaw, D. S., Dishion, T. J., Supplee, L., Gardner, F., & Arnds, K. (2006). Randomized trial of a family-centered approach to the prevention of early conduct problems: 2-year effects of the family check-up in early childhood. Journal of Consulting and Clinical Psychology, 74, 1–9.CrossRefPubMedGoogle Scholar
  69. Sharma, S., & Sharma, M. (2010). Globalization, threatened identities, coping and well-being. Psychological Studies, 55, 313–322.CrossRefGoogle Scholar
  70. Shonkoff, J. P., Boyce, W. T., & McEwen, B. S. (2009). Neuroscience, molecular biology, and the childhood roots of health disparities. JAMA, 301, 2252–2259.CrossRefPubMedGoogle Scholar
  71. Spoth, R., & Greenberg, M. (2011). Impact challenges in community science-with-practice: Lessons from PROSPER on transformative practitioner-scientist partnerships and prevention infrastructure development. American Journal of Community Psychology, 48, 106–119.CrossRefPubMedPubMedCentralGoogle Scholar
  72. Spoth, R., Guyll, M., Redmond, C., Greenberg, M., & Feinberg, M. (2011). Six-year sustainability of evidence-based intervention implementation quality by community-university partnerships: The PROSPER study. American Journal of Community Psychology, 48, 412–425.CrossRefPubMedPubMedCentralGoogle Scholar
  73. Stokols, D. (1992). Establishing and maintaining healthy environments: toward a social ecology of health promotion. American Psychologist, 47, 6–22.Google Scholar
  74. Substance Abuse and Mental Health Services Administration. (2014). Results from the 2013 National Survey on Drug Use and Health: Summary. Rockville, MD: SAMHSA.Google Scholar
  75. U. S. Department of Health and Human Services. (2012). Preventing tobacco use among youth and young adults: A report of the Surgeon General. Atlanta, GA: USDHHS.Google Scholar
  76. United States v. Philip Morris USA, Inc. (2006). Civil Action No. 99–2496 (DDC 2012), Final Order.Google Scholar
  77. Valentine, J. C., Biglan, A., Boruch, R. F., Castro, F. G., Collins, L. M., Flay, B. R., et al. (2011). Replication in prevention science. Prevention Science, 12, 103–117.CrossRefPubMedGoogle Scholar
  78. Wagenaar, A. C., & Burris, S. C. (Eds.). (2013). Public health law research: Theory and methods. New York: Wiley & Sons.Google Scholar
  79. Wagenaar, A. C., Maldonado-Molina, M., & Wagenaar, B. H. (2009). Effects of alcohol tax increases on disease mortality in Alaska: Time-series analyses from 1976 to 2004. 99, 1464–1470.Google Scholar
  80. Warren, K. (2014). A fighting chance. New York, NY: Metropolitan Books.Google Scholar
  81. Webster-Stratton, C., & Mihalic, S. F. (2001). The incredible years: Parent, teacher and child training series. Boulder, CO: Center for the Study and Prevention of Violence.Google Scholar
  82. Wilkinson, R., & Pickett, K. (2009). The spirit level: Why greater equality makes societies stronger. London: Bloomsbury Press.Google Scholar
  83. Wilson, D. S. (2011). The neighborhood project: Using evolution to improve my city, one block at a time. New York: Little, Brown.Google Scholar
  84. Wilson, D. S., Hayes, S. C., Biglan, A., & Embry, D. D. (2014). Evolving the future: Toward a science of intentional change. Behavioral and Brain Sciences, 37, 395–416.CrossRefPubMedPubMedCentralGoogle Scholar
  85. Yoshikawa, H., Aber, J. L., & Beardslee, W. R. (2012). The effects of poverty on the mental, emotional, and behavioral health of children and youth: Implications for prevention. American Psychologist, 67, 272–284.CrossRefPubMedGoogle Scholar

Copyright information

© Society for Prevention Research 2016

Authors and Affiliations

  1. 1.Oregon Research InstituteEugeneUSA

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