Prevention Science

, 12:103 | Cite as

Replication in Prevention Science

  • Jeffrey C. Valentine
  • Anthony Biglan
  • Robert F. Boruch
  • Felipe González Castro
  • Linda M. Collins
  • Brian R. Flay
  • Sheppard Kellam
  • Eve K. Mościcki
  • Steven P. Schinke


Replication research is essential for the advancement of any scientific field. In this paper, we argue that prevention science will be better positioned to help improve public health if (a) more replications are conducted; (b) those replications are systematic, thoughtful, and conducted with full knowledge of the trials that have preceded them; and (c) state-of-the art techniques are used to summarize the body of evidence on the effects of the interventions. Under real-world demands it is often not feasible to wait for multiple replications to accumulate before making decisions about intervention adoption. To help individuals and agencies make better decisions about intervention utility, we outline strategies that can be used to help understand the likely direction, size, and range of intervention effects as suggested by the current knowledge base. We also suggest structural changes that could increase the amount and quality of replication research, such as the provision of incentives and a more vigorous pursuit of prospective research registers. Finally, we discuss methods for integrating replications into the roll-out of a program and suggest that strong partnerships with local decision makers are a key component of success in replication research. Our hope is that this paper can highlight the importance of replication and stimulate more discussion of the important elements of the replication process. We are confident that, armed with more and better replications and state-of-the-art review methods, prevention science will be in a better position to positively impact public health.


Replication Reproducibility Systematic Review Meta-Analysis Effectiveness 


Author Note

This paper is the result of the deliberations of the Standards of Evidence Taskforce, convened and funded by the Society for Prevention Research (Brian R. Flay, Chair). The Board of Directors of the Society for Prevention Research is pleased to have supported the preparation of this paper in hopes that it will stimulate further discussion about the importance of replication.

The views expressed in this paper are the authors’, and do not necessarily reflect the views of the authors’ institutions or the Society for Prevention Research. With the exception of the first author, order of authorship is alphabetical.

We thank Richard Catalano, Harris Cooper, Adam Haldahl, Mark Lipsey, and Patrick Tolan for their valuable feedback on earlier versions of this paper, and Kirsten Sundell for editing the final manuscript.


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Copyright information

© Society for Prevention Research 2011

Authors and Affiliations

  • Jeffrey C. Valentine
    • 1
  • Anthony Biglan
    • 2
  • Robert F. Boruch
    • 3
  • Felipe González Castro
    • 4
  • Linda M. Collins
    • 5
  • Brian R. Flay
    • 6
  • Sheppard Kellam
    • 7
  • Eve K. Mościcki
    • 8
  • Steven P. Schinke
    • 9
  1. 1.University of LouisvilleLouisvilleUSA
  2. 2.Oregon Research InstituteEugeneUSA
  3. 3.University of PennsylvaniaPhiladelphiaUSA
  4. 4.Arizona State UniversityTempeUSA
  5. 5.Pennsylvania State UniversityUniversity ParkUSA
  6. 6.Oregon State UniversityCorvallisUSA
  7. 7.American Institutes for ResearchWashingtonUSA
  8. 8.American Psychiatric Institute for Research and EducationArlingtonUSA
  9. 9.Columbia UniversityNew YorkUSA

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