Artificial photoactive proteins
- 180 Downloads
Solar power is the most abundant source of renewable energy. In this respect, the goal of making photoactive proteins is to utilize this energy to generate an electron flow. Photosystems have provided the blueprint for making such systems, since they are capable of converting the energy of light into an electron flow using a series of redox cofactors. Protein tunes the redox potential of the cofactors and arranges them such that their distance and orientation are optimal for the creation of a stable charge separation. The aim of this review is to present an overview of the literature with regard to some elegant functional structures that protein designers have created by introducing cofactors and photoactivity into synthetic proteins.
KeywordsProtein design Photosystem Cofactor binding Chlorophyll Electron transfer Reaction center
Primary electron donor
Water-soluble Chl binding proteins
This work was supported in part by Nova Southeastern University Faculty Research and Development Grant.
- Kehoe JW, Meadows KA, Parkesloach PS et al (1998) Reconstitution of core light-harvesting complexes of photosynthetic bacteria using chemically synthesized polypeptides. 2. Determination of structural features that stabilize complex formation and their implications for the structure of the subunit complex. Biochemistry 37:3418–3428. doi: 10.1021/bi9722709 PubMedCrossRefGoogle Scholar
- Wakao N, Yokoi N, Isoyama N et al (1996) Discovery of natural photosynthesis using Zn-containing bacteriochlorophyll in an aerobic bacterium Acidiphilium rubrum. Plant Cell Physiol 37:889–893Google Scholar