Phytochemistry Reviews

, Volume 9, Issue 3, pp 413–424 | Cite as

Tricin—a potential multifunctional nutraceutical

  • Jian-Min Zhou
  • Ragai K. Ibrahim


This review throws light on the natural occurrence and distribution of tricin (5,7,4′-trihydroxy-3′,5′-dimethoxyflavone) and its conjugated forms, as more common natural plant constituents than previously known. It examines the current literature dealing with its biosynthesis, regulation, biological significance, pharmacological effects, and potential role as a chemopreventive and anticancer agent. Because of its common occurrence in cereal grain plants and the wide spectrum of its health promoting effects, a metabolic engineering strategy is proposed to produce tricin in sufficient amounts for further experimentation, and increase its accumulation in wheat grain endosperm as a nutraceutical.


Tricin Natural occurrence Biology Metabolic engineering Nutraceutical 



We wish to thank the Natural Sciences and Engineering Research Council (NSERC) of Canada for financial support of the work cited from the authors’ laboratory.


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© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  1. 1.Plant Biochemistry Laboratory and Centre for Structural and Functional Genomics, Biology DepartmentConcordia UniversityMontrealCanada

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