Effect of clinical pharmacist intervention on the treatment of acute pancreatitis

  • Jia-Li Niu
  • Yun-Long Ding
  • Feng Ju
  • Tong Lu
  • Ting Xue
  • Kai-Xia Chen
  • Hong-Jun Chen
  • Guang-Yu ZhaoEmail author
Research Article


Background The participation of clinical pharmacists in the treatment of acute pancreatitis has rarely been reported. Objective The aim of this study was to retrospectively evaluate the impact of intervention of clinical pharmacists on the treatment of acute pancreatitis. Setting An academic teaching hospital in Taizhou, Jiangsu, China. Method Two hundred and twenty-eight patients with acute pancreatitis were retrospectively enrolled from July 2017 to July 2018 and divided into an intervention group (n = 119) and a control group (n = 109) according to whether a clinical pharmacist was involved. No significant differences in the baseline clinical characteristics were found between the groups. Clinical pharmacists participated in drug formulation and adjustment, pharmaceutical care, and follow-up. Main outcome measure Clinical outcomes, average hospital stays, costs, incidence of adverse drug reactions, 1-month subsequent visit rate, and patient satisfaction between the two groups were measured. Results The clinical symptoms of patients in both groups were relieved after treatment. There were no significant differences between the groups in computed tomography grades after treatment, incidence of adverse drug reactions, or average hospital stays. However, the intervention group had lower total costs of hospitalization, drugs and antibiotics but higher rates of 1-month subsequent visits and satisfaction compared with the control group. Conclusion The intervention of clinical pharmacists in the treatment of acute pancreatitis can effectively reduce costs of hospitalization, drug and antibiotics and improve follow-up compliance and patient satisfaction.


Acute pancreatitis China Clinical pharmacist Pharmaceutical care Pharmacist intervention 



We thank all the medical staff for their participation in this study.


This work was funded by the Guidance plan for social development of Taizhou Municipal Science and Technology (ssf20160141). The funder had no role in the study design, data collection, data analysis, data interpretation, writing of the report, decision to publish, or preparation of the manuscript.

Conflicts of interest

No conflicts of interest are declared.

Supplementary material

11096_2019_931_MOESM1_ESM.xlsx (30 kb)
Supplementary material 1 (XLSX 29 kb)


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Clinical Pharmacy, JingJiang People’s Hospitalthe Seventh Affiliated Hospital of Yangzhou UniversityJingjiangChina
  2. 2.Department of Neurology, JingJiang People’s Hospitalthe Seventh Affiliated Hospital of Yangzhou UniversityJingjiangChina
  3. 3.Department of Pharmacy, JingJiang People’s Hospitalthe Seventh Affiliated Hospital of Yangzhou UniversityJingjiangChina

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