International Journal of Clinical Pharmacy

, Volume 38, Issue 5, pp 1063–1068 | Cite as

Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool

  • Eline TommeleinEmail author
  • Els Mehuys
  • Mirko Petrovic
  • Annemie Somers
  • Charlotte Van Damme
  • Eva Pattyn
  • Kristof Mattelin
  • Koen Boussery
Short Research Report


Background The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP³S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP). Objective We aimed (1) to determine PIP prevalence in older nursing home (NH) residents with polypharmacy using the GheOP³S-tool and (2) to identify those PIPs that are most frequently detected. Method A cross-sectional study was carried out between February and June 2014 in 10 NHs in Belgium, supplied by a community pharmacy chain. For each NH, 40 residents (≥70 years, using ≥5 chronic drugs) were included. PIP prevalence was determined using the GheOP³S-tool. Results 400 NH residents were included [mean age (±SD) 86.2 (±6.3) years; median number of drugs (±IQR) 10 (7–12)]. A total of 1728 PIPs were detected in 387 (97 %) participants (Median 4; IQR 2–6). The most prevalent items can be assigned to three categories: long-term use of central nervous system drugs (i.e. benzodiazepines, antidepressants and antipsychotics), use of anticholinergic drugs (mutual combinations and with underlying constipation/dementia) and underuse of osteoporosis prophylaxis. Conclusion Screening for PIP by means of the GheOP³S-tool revealed a high prevalence of PIP among older NH residents with polypharmacy. This finding urges for initiatives on the patient-level, but also on a broader, institutional level.


Aged Belgium GheOP³S Inappropriate prescribing Nursing homes PIP 



We would like to thank the community pharmacy chain for providing us with the dataset and assistance when case clarification was needed.


No financial remuneration was received for the study.

Conflicts of interest

All authors completed the ICMJE-form. No competing interests were declared.

Supplementary material

11096_2016_366_MOESM1_ESM.docx (22 kb)
Supplementary material 1 (DOCX 21 kb)


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Copyright information

© Springer International Publishing 2016

Authors and Affiliations

  • Eline Tommelein
    • 1
    Email author
  • Els Mehuys
    • 1
  • Mirko Petrovic
    • 2
  • Annemie Somers
    • 3
  • Charlotte Van Damme
    • 1
  • Eva Pattyn
    • 1
  • Kristof Mattelin
    • 1
  • Koen Boussery
    • 1
  1. 1.Pharmaceutical Care Unit, Faculty of Pharmaceutical SciencesGhent UniversityGhentBelgium
  2. 2.Department of Internal Medicine, Faculty of Medicine and Health SciencesGhentBelgium
  3. 3.Department of PharmacyGhent University HospitalGhentBelgium

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