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International Journal of Clinical Pharmacy

, Volume 34, Issue 6, pp 828–831 | Cite as

Drug-related problems in patients with ischemic stroke in hospital

  • Carina HohmannEmail author
  • Tobias Neumann-Haefelin
  • Jürgen M. Klotz
  • Annette Freidank
  • Roland Radziwill
Short Research Report

Abstract

Background Drug therapy is getting more complex, thus making it more challenging to prescribe appropriate drug therapy. Accordingly, in clinical practice, a wide range of drug-related problems (DRP) may arise; they are relatively common in hospitalised patients and can result in patient morbidity and mortality, and increased costs. Objective The objective was to investigate the nature and frequency of DRPs along with pharmaceutical interventions to address them in patients with ischemic stroke from hospital admission to discharge. Method From January to June 2011 patients with ischemic stroke, who were taking >2 drugs during hospital stay and at discharge, were recruited. A clinical pharmacist performed medication reconciliation on admission, and checked the medication records during the hospital stay regularly. DRPs were categorized by APS-Doc. Results In total, DRPs occurred in 105/155 (67.7 %) patients: Overall 271 DRPs were documented, with a mean of 1.8 ± 2.0 DRPs per patient. The DRPs occurred mainly in the categories “drug”, “indication”, and “dosage”. Conclusion In conclusion, DRPs are relatively common in hospitalised patients and may occur at any part of the prescribing process. The clinical pharmacist can provide a valuable contribution in the multidisciplinary team to an optimized pharmacotherapy in patients with ischemic stroke.

Keywords

APS-Doc Drug-related problems Germany Hospital setting Ischemic stroke Pharmaceutical intervention 

Abbreviations

DRP

Drug-related problem

IQR

Interquartile range

MDRD

Modification of Diet in Renal Disease

n/a

Not available

SD

Standard deviation

TIA

Transient ischemic attack

Notes

Acknowledgments

We would like to thank the participating patients and physicians who supported our study.

Funding

None.

Conflicts of interest

None.

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Carina Hohmann
    • 1
    • 2
    Email author
  • Tobias Neumann-Haefelin
    • 2
  • Jürgen M. Klotz
    • 2
  • Annette Freidank
    • 1
  • Roland Radziwill
    • 1
  1. 1.Department of PharmacyKlinikum Fulda gAGFuldaGermany
  2. 2.Department of NeurologyKlinikum Fulda gAGFuldaGermany

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