International Journal of Clinical Pharmacy

, Volume 34, Issue 2, pp 290–294 | Cite as

Impact of the pharmacist on a multidisciplinary team in an antimicrobial stewardship program: a quasi-experimental study

  • Lucas MagedanzEmail author
  • Erci Maria Silliprandi
  • Rodrigo Pires dos Santos
Short Research Report


Background Antimicrobial stewardship programs (ASP) have been implemented to promote rational use of antimicrobial drugs. Multidisciplinary teams are needed to form effective committees. Objective Assess the impact of ASP, with and without the presence of a pharmacist, in a cardiology hospital in Brazil. Methods The program started with an infectious disease (ID) physician, and after 22 months, a pharmacist started to work in the ASP team. We present data related to: stage 1—before the program implementation; stage 2—with the ID physician; and stage 3 with the inclusion of a pharmacist. Analysis was made by segmented regression of time series. Results After the start of ASP there was a significant reduction of consumption of all antimicrobials. The pharmacist contributed to the significant reduction in consumption of fluoroquinolones, clindamycin and ampicillin/sulbactam and in increase in total cephalosporins use in stage 3. Adherence rate to the ASP team recommendations was 64.1%. There was a significant reduction of 69% in hospital antibiotics costs. Conclusion A non-expensive ASP in a limited resource country resulted in reductions in antimicrobial consumption and costs. The multidisciplinary team contributed to maximize the impact of interventions.


Antibiotics Antimicrobial stewardship program Brazil Infection control pharmacist Pharmacopidemiology 



We would like to thank the Instituto de Cardiologia—Fundação Universitária de Cardiologia, for their administrative support, and to Anderlise Luvizetto, Juliana Guedes, Otávio Fontoura Carvalho and Thalita Jacoby for their contribution to this study.



Conflicts of interest

The authors declare no conflicts of interests with regard to the material published in this article.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • Lucas Magedanz
    • 1
    Email author
  • Erci Maria Silliprandi
    • 1
  • Rodrigo Pires dos Santos
    • 1
    • 2
    • 3
  1. 1.Hospital Infection Control Service, Instituto de Cardiologia FundaçãoUniversitária de Cardiologia de Porto AlegrePorto AlegreBrazil
  2. 2.Infectious Disease Service, Hospital de Clínicas de Porto AlegrePorto AlegreBrazil
  3. 3.Hospital Infection Control Committee, Hospital de Clínicas de Porto AlegrePorto AlegreBrazil

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