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International Journal of Clinical Pharmacy

, Volume 33, Issue 6, pp 964–973 | Cite as

Perceptions and attitudes of Jordanian paediatricians towards off-label paediatric prescribing

  • Tareq L. MukattashEmail author
  • Mayyada Wazaify
  • Najwa Khuri-Boulos
  • Anan Jarab
  • Ahmed F. Hawwa
  • James C. McElnay
Research Article

Abstract

Objective To assess current experiences and attitudes of hospital based paediatricians towards off-label medicine prescribing. Setting Paediatric hospital wards and out-patient clinics. Design A prospective, questionnaire based study. Results A 30 item questionnaire was sent to 300 hospital based paediatricians and 250 (83%) were returned completed. Over 69% of responders were familiar with the term off-label medicines. However, only 28% were knowingly prescribing off-label medicines to children. The majority of respondents (90%) expressed concerns about the safety and efficacy of off-label medicines. Only 15% had observed Adverse Drug Reactions, and 31% a treatment failure. The vast majority of respondents (83%) did not obtain informed consent or tell parents they were prescribing off label medicines to their children. Conclusions Off-label prescribing of medicines to children is a familiar concept to the majority of paediatricians in Jordan although only a smaller number are aware that it is common in their practice. Respondents showed concern about off label prescribing, although the majority do not consider it necessary to inform parents. More comprehensive research is needed in this area in Jordan and other Middle Eastern countries.

Keywords

Children Jordan Off-label prescribing Paediatricians Perceptions Prescribing 

Notes

Acknowledgments

All the paediatricians who participated in this study.

Funding

No external funding was obtained for this study.

Conflicts of interest

None declared.

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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Tareq L. Mukattash
    • 1
    Email author
  • Mayyada Wazaify
    • 2
  • Najwa Khuri-Boulos
    • 3
  • Anan Jarab
    • 4
  • Ahmed F. Hawwa
    • 5
  • James C. McElnay
    • 5
  1. 1.Department of Clinical Pharmacy, Faculty of PharmacyJordan University of Science and TechnologyIrbidJordan
  2. 2.Department of Biopharmaceutics and Clinical Pharmacy, Faculty of PharmacyUniversity of JordanAmmanJordan
  3. 3.Department of Paediatrics, Faculty of MedicineUniversity of JordanAmmanJordan
  4. 4.Department of Clinical Pharmacy, Faculty of PharmacyAl-Zaytoonah University of JordanAmmanJordan
  5. 5.Clinical and Practice Research Group, School of Pharmacy, Medical Biology CentreQueen’s University BelfastBelfastUK

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