Interaction between methotrexate and omeprazole in an adolescent with leukemia: a case report
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We present a case of severe mucositis due to a drug–drug interaction between methotrexate (MTX) and omeprazole in an adolescent with Acute Lymphatic Leukemia (ALL). In view of the prevalence of MTX in many cytotoxic protocols, and the frequent use of omeprazole in the (ambulatory) oncology setting, we believe that this case-report is worth mentioning.
KeywordsDrug-drug interaction Leukemia Methotrexate Omeprazole Pediatric oncology
Conflicts of interest
There are no conflicts of interest nor funding.
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