Levetiracetam in three cases of progressive myoclonus epilepsy
- 69 Downloads
We present three unrelated cases of genetically confirmed progressive myoclonic epilepsy of the Unverricht–Lundborg type who were treated with Levetiracetam as adjunctive therapy for their myoclonus. All cases responded with decrease of their myoclonus and improvement of quality of life. Two were able to return to or continue their employment. Patients tolerated the drug well without side effects reported. Levetiracetam appears to be a useful antimyoclonic agent in cases of progressive myoclonic epilepsy and should be considered for adjunctive therapy.
KeywordsEpilepsy Levetiracetam Progressive Myoclonus Unverricht–Lundborg epilepsy
Unable to display preview. Download preview PDF.
The authors of this manuscript report no conflicts of interest.
- 9.Ben-Menachem E, Falter U, for the European Levetiracetam Study Group. Efficacy and tolerability of levetiracetam 3000 mg/day in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. Epilepsia 2000;41:1276–83.Google Scholar
- 10.Kasteleijn-Nolst Trenite DGA, Hirsch E. Levetiracetam: preliminary efficacy in generalized seizures. Epileptic Disord 2003;5 Suppl 1:S39–S44.Google Scholar