Pharmacy World and Science

, Volume 28, Issue 4, pp 248–256

Differences in adherence and motivation to HIV therapy—two independent assessments in 1998 and 2002

  • Björn Södergård
  • Margit Halvarsson
  • Stefan Lindbäck
  • Anders Sönnerborg
  • Mary P. Tully
  • Åsa Kettis Lindblad
Research Article

DOI: 10.1007/s11096-006-9036-4

Cite this article as:
Södergård, B., Halvarsson, M., Lindbäck, S. et al. Pharm World Sci (2006) 28: 248. doi:10.1007/s11096-006-9036-4

Abstract

Objective

The aim of this study was to compare the level of adherence and motivation in two independent cross-sectional samples of HIV-infected patients conducted in 1998 and 2002, and to investigate the relationship between adherence and motivation.

Method

Consecutive HIV-infected patients on treatment at a Swedish clinic were asked to complete an anonymous questionnaire. In 1998, 60 patients participated and in 2002, 53 participated. In 2002, the 9-item Morisky Medication Adherence Scale (MMAS) was added to the questionnaire set.

Main outcome measure

Self-reported adherence and motivation.

Results

In 1998, 28.1% of the respondents were considered adherent, while the corresponding proportion was 57.4% in 2002 (P = 0.002). The mean summary score for MMAS was 10.7 in 2002 (13 = perfect adherence). The proportion considered motivated were 22.4% in the 1998 survey and 41.3% in 2002 (P = 0.038). Of the respondents considered motivated in the 2002 survey, 46.7% scored the maximum summary score on the MMAS, while 8.7% of the non-motivated respondents did so (P = 0.016).

Conclusion

The respondents in 2002 were more adherent and motivated than the respondents in 1998 and a relationship between motivation and adherence was found. The difference in adherence and motivation might be due to a new treatment model at the clinic.

Keywords

Acquired immunodeficiency syndrome AIDS HIV Highly active antiretroviral therapy MMAS Patient adherence Patient compliance Patient motivation Pharmacotherapy Sweden 

Copyright information

© Springer Science+Business Media B.V. 2006

Authors and Affiliations

  • Björn Södergård
    • 1
    • 2
  • Margit Halvarsson
    • 3
  • Stefan Lindbäck
    • 3
  • Anders Sönnerborg
    • 4
  • Mary P. Tully
    • 1
    • 5
  • Åsa Kettis Lindblad
    • 1
  1. 1.Pharmaceutical Outcomes Research Group, Department of PharmacyUppsala UniversityUppsalaSweden
  2. 2.Hospital pharmacyKarolinska University Hospital – HuddingeStockholmSweden
  3. 3.HIV ClinicKarolinska University HospitalHuddingeSweden
  4. 4.Divisions of Infectious Diseases and Clinical Virology, Karolinska InstitutetKarolinska University HospitalHuddingeSweden
  5. 5.School of Pharmacy and Pharmaceutical SciencesUniversity of ManchesterManchesterUK

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