Pharmacy World and Science

, Volume 28, Issue 3, pp 123–125

Bacterial meningitis associated with infliximab

CASE REPORT

Abstract

We report an episode of bacterial meningitis in a 45 year-old woman, who was treated with infliximab for Wegener’s granulomatosis. This patient presented with the classic clinical presentation of acute meningitis: the triad of fever, neck stiffness, and an altered mental state that appeared 6 months after the infliximab initiation. A computed tomographic (CT) scan of the head showed cerebral edema and Streptococcus peumoniae was isolated from blood and CSF cultures. Prompt diagnosis and early treatment improved the outcome of this patient.

Keywords

Infliximab Meningitis TNF-α Wegener’s granulomatosis 

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Copyright information

© Springer Science+Business Media B.V. 2006

Authors and Affiliations

  1. 1.Department of Internal Medicine F-Nahariya Hospital, B. Rappaport Faculty of MedicineWestern Galilee HospitalTechnion, NahariyaIsrael

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