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Pharmacy World & Science

, 29:43 | Cite as

Pharmacovigilance and pharmacoepidemiology of drugs in a Mexican pediatric hospital. A proposed guide

  • Hugo Juárez-OlguínEmail author
  • Gabriela Pérez-Guillé
  • Janett Flores-Pérez
Article

Abstract

We describe the procedures of pharmacovigilance (PV) and pharmacoepidemiology (PE) of drugs in a pediatric hospital. These activities contribute to the detection and registration of adverse drug reactions and to determine the patterns of drug prescription among children attended at the hospital. The PV activities show that there is a relation between an increase in incidence of adverse drug reactions and the prescription of a larger number of drugs. The PE activities reveal that antibiotics are the most frequently prescribed drugs and next are drugs used for gastrointestinal diseases. Since PV and PE activities were initiated at our hospital, they have contributed to a more adequate use of drugs in children. As a conclusion of these activities, it could be that if the PE of a hospital is known, drug consumption can be optimally planned. PV and PE demonstrate that, if polytherapy is not necessary, it must be avoided. Finally, the present guide can be adopted to initiate PV and PE at a hospital.

Keywords

Drugs Hospital pharmacy Pediatrics Pharmacoepidemiology Pharmacovigilance 

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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • Hugo Juárez-Olguín
    • 1
    • 2
    • 3
    Email author
  • Gabriela Pérez-Guillé
    • 1
  • Janett Flores-Pérez
    • 3
  1. 1.Laboratory of Pharmacology, National Institute of PediatricsMexico cityMexico
  2. 2.Laboratory of Pharmacology, Instituto Nacional de PediatríaMexico cityMexico
  3. 3.Department of Pharmacology, Medicine FacultyUniversidad Nacional Autónoma de MéxicoMexico cityMexico

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