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Pharmaceutical Research

, Volume 34, Issue 6, pp 1149–1151 | Cite as

Insights and Lessons from a Scientific Conference on Non-Invasive Delivery of Macromolecules

  • Ronak Savla
  • Randall J. Mrsny
  • Kinam Park
  • Isabelle Aubert
  • Cornell Stamoran
Perspective

Abstract

A growing share of the pharmaceutical development pipeline is occupied by macromolecule drugs, which are primarily administered by injection. Despite decades of attempts, non-invasive delivery of macromolecules has seen only a few success stories. Potential benefits of non-invasive administration include better patient acceptance and adherence and potentially better efficacy and safety. Greater inter-disciplinary dialogue and collaboration are integral to realizing these benefits.

KEY WORDS

blood-brain barrier drug delivery in vitro models macromolecules permeation enhancers 

Notes

Acknowledgments and Disclosures

RS and CS are employees of Catalent Pharma Solutions.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Catalent Pharma SolutionsSomersetUSA
  2. 2.Department of Pharmacy & PharmacologyUniversity of BathBathUK
  3. 3.Departments of Biomedical Engineering and PharmaceuticsPurdue UniversityWest LafayetteUSA
  4. 4.Department of Laboratory Medicine and PathobiologyUniversity of TorontoTorontoCanada

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