Pharmaceutical Chemistry Journal

, Volume 51, Issue 9, pp 800–805 | Cite as

An Extract of Lychnis chalcedonica as the Basis for Developing a Novel Ecdysteroid-Containing Formulation with Actoprotector Activity

  • M. B. Plotnikov
  • L. N. Zibareva
  • A. S. Vasil’ev
  • O. I. Aliev
MEDICINAL PLANTS
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A novel ecdysteroid-containing pharmaceutical substance – Lychnis chalcedonica extract – was developed. The phytoecdysteroid composition of the ethanolic extract was determined. Courses of intragastric administration of Lychnis chalcedonica extract (150 mg/kg) were accompanied by anabolic effects in both trained and untrained animals. The actoprotector properties of the Lychnis chalcedonica extract and improvements in carbohydrate metabolism on exhaustive physical exertion were seen only in trained animals. Lychnis chalcedonica extract is a pharmaceutical substance with potential for use as the basis for developing formulations with actoprotector activity.

Keywords

Lychnis chalcedonica extract ecdysteroids actoprotector activity 
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • M. B. Plotnikov
    • 1
  • L. N. Zibareva
    • 2
  • A. S. Vasil’ev
    • 1
  • O. I. Aliev
    • 1
  1. 1.E. D. Goldberg Science Research Institute of Pharmacology and Regenerative MedicineTomsk National Medical Research CenterTomskRussia
  2. 2.Tomsk National State Research UniversityTomskRussia

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