A series of new urea derivatives were synthesized from (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediol and their antimicrobial activities were studied. Of the eight ureas synthesized here, only one compound had weak antimicrobial activity in relation to B. cereus and Candida spp.
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The authors would like to thank Fernand Leal, France, for assistance with these studies and constructive discussion of the results.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 1, pp. 12 – 14, January, 2015.
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Madesclaire, M., Coudert, P., Lyamin, A.V. et al. Synthesis and Antimicrobial Activity of New Ureas from (1S,2S)-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol. Pharm Chem J 49, 10–12 (2015). https://doi.org/10.1007/s11094-015-1213-0
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DOI: https://doi.org/10.1007/s11094-015-1213-0