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Pharmaceutical Chemistry Journal

, Volume 48, Issue 3, pp 214–216 | Cite as

Effects of Processing Regimes on the Loss of Disperse Pharmaceutical Materials from Pulsatile Layers

  • M. S. VasilishinEmail author
  • O. S. Ivanov
  • A. A. Kukhlenko
  • S. E. Orlov
  • A. G. Karpov
Article
  • 52 Downloads

The effects of pulsation frequency, fluidizing agent speed, and layer height on the loss of medicinal ascorbic acid and gamma-aminobutyric acid (Aminalon) from a pulsatile layer device were studied. An empirical relationship is proposed for estimation of loss.

Keywords

medicinal ascorbic acid Aminalon pulsatile layer loss 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • M. S. Vasilishin
    • 1
  • O. S. Ivanov
    • 1
  • A. A. Kukhlenko
    • 1
  • S. E. Orlov
    • 1
  • A. G. Karpov
    • 1
  1. 1.Institute of Problems of Chemical and Energy Technologies, Siberian BranchRussian Academy of SciencesBiiskRussia

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